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1000 Titel
  • MRI follow-up after magnetic resonance-guided focused ultrasound for non-invasive thalamotomy: the neuroradiologist’s perspective
1000 Autor/in
  1. Keil, Vera C |
  2. Borger, Valeri |
  3. Purrer, Veronika |
  4. Groetz, Simon F. |
  5. Scheef, Lukas |
  6. Boecker, Henning |
  7. Schild, Hans H. |
  8. Kindler, Christine |
  9. Schmitt, Angelika |
  10. Solymosi, Laszlo |
  11. Wüllner, Ullrich |
  12. Pieper, Claus C. |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-05-03
1000 Erschienen in
1000 Quellenangabe
  • 62(9):1111-1122
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00234-020-02433-9 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7410861/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!Magnetic resonance-guided focused ultrasound (MRgFUS) systems are increasingly used to non-invasively treat tremor; consensus on imaging follow-up is poor in these patients. This study aims to elucidate how MRgFUS lesions evolve for a radiological readership with regard to clinical outcome.!##!Methods!#!MRgFUS-induced lesions and oedema were retrospectively evaluated based on DWI, SWI, T2-weighted and T1-weighted 3-T MRI data acquired 30 min and 3, 30 and 180 days after MRgFUS (n = 9 essential tremor, n = 1 Parkinson's patients). Lesions were assessed volumetrically, visually and by ADC measurements and compared with clinical effects using non-parametric testing.!##!Results!#!Thirty minutes after treatment, all lesions could be identified on T2-weighted images. Immediate oedema was rare (n = 1). Lesion volume as well as oedema reached a maximum on day 3 with a mean lesion size of 0.4 ± 0.2 cm!##!Conclusion!#!In conclusion, cerebral MRgFUS lesions variably shrink over months. SWI is the sequence of choice to identify lesions after 6 months. Lesion volume is arguably associated with intermediate-term outcome.
1000 Sacherschließung
lokal Female [MeSH]
lokal High-intensity focused ultrasound ablation
lokal Follow-Up Studies [MeSH]
lokal Parkinson disease
lokal Aged [MeSH]
lokal Essential Tremor/diagnostic imaging [MeSH]
lokal Essential tremor
lokal Humans [MeSH]
lokal Retrospective Studies [MeSH]
lokal Parkinson Disease/therapy [MeSH]
lokal Thalamus/diagnostic imaging [MeSH]
lokal Ultrasonic Therapy [MeSH]
lokal Parkinson Disease/diagnostic imaging [MeSH]
lokal Male [MeSH]
lokal Magnetic Resonance Imaging, Interventional [MeSH]
lokal Essential Tremor/therapy [MeSH]
lokal Magnetic resonance imaging
lokal Diagnostic Neuroradiology
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-8699-3506|https://frl.publisso.de/adhoc/uri/Qm9yZ2VyLCBWYWxlcmk=|https://frl.publisso.de/adhoc/uri/UHVycmVyLCBWZXJvbmlrYQ==|https://frl.publisso.de/adhoc/uri/R3JvZXR6LCBTaW1vbiBGLg==|https://frl.publisso.de/adhoc/uri/U2NoZWVmLCBMdWthcw==|https://frl.publisso.de/adhoc/uri/Qm9lY2tlciwgSGVubmluZw==|https://frl.publisso.de/adhoc/uri/U2NoaWxkLCBIYW5zIEgu|https://frl.publisso.de/adhoc/uri/S2luZGxlciwgQ2hyaXN0aW5l|https://frl.publisso.de/adhoc/uri/U2NobWl0dCwgQW5nZWxpa2E=|https://frl.publisso.de/adhoc/uri/U29seW1vc2ksIExhc3psbw==|https://frl.publisso.de/adhoc/uri/V8O8bGxuZXIsIFVsbHJpY2g=|https://frl.publisso.de/adhoc/uri/UGllcGVyLCBDbGF1cyBDLg==
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1000 Erstellt am 2023-11-17T04:34:12.050+0100
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