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1000 Titel
  • Dual-source computed tomography of the lung with spectral shaping and advanced iterative reconstruction: potential for maximum radiation dose reduction
1000 Autor/in
  1. Wetzl, Matthias |
  2. May, Matthias S. |
  3. Weinmann, Daniel |
  4. Hammon, Matthias |
  5. Treutlein, Christoph |
  6. Zeilinger, Martin |
  7. Kiefer, Alexander |
  8. Trollmann, Regina |
  9. Woelfle, Joachim |
  10. Uder, Michael |
  11. Rompel, Oliver |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-06-17
1000 Erschienen in
1000 Quellenangabe
  • 50(9):1240-1248
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00247-020-04714-0 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7398955/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Radiation dose at CT should be as low as possible without compromising diagnostic quality.!##!Objective!#!To assess the potential for maximum dose reduction of pediatric lung dual-source CT with spectral shaping and advanced iterative reconstruction (ADMIRE).!##!Materials and methods!#!We retrospectively analyzed dual-source CT acquisitions in a full-dose group (FD: 100 kV, 64 reference mAs) and in three groups with spectral shaping and differing reference mAs values (Sn: 100 kV, 96/64/32 reference mAs), each group consisting of 16 patients (age mean 11.5 years, standard deviation 4.8 years, median 12.8 years, range 1.3-18 years). Advanced iterative reconstruction of images was performed with different strengths (FD: ADMIRE Level 2; Sn: ADMIRE Levels 2, 3 and 4). We analyzed dose parameters and measured noise. Diagnostic confidence and detectability of lung lesions as well as anatomical structures were assessed using a Likert scale (from 1 [unacceptable] to 4 [fully acceptable]).!##!Results!#!Compared to full dose, effective dose was reduced to 16.7% in the Sn 96 group, 11.1% in Sn64, and 5.5% in Sn32 (P<0.001). Noise values of Sn64!##!Conclusion!#!In pediatric lung dual-source CT, spectral shaping together with ADMIRE 4 enable radiation dose reduction to about 10% of a full-dose protocol while maintaining an acceptable diagnostic quality.
1000 Sacherschließung
lokal Adolescent [MeSH]
lokal Female [MeSH]
lokal Adolescents
lokal Lung Diseases/diagnostic imaging [MeSH]
lokal Advanced iterative reconstruction
lokal Humans [MeSH]
lokal Radiation dose reduction
lokal Retrospective Studies [MeSH]
lokal Tin prefiltration
lokal Tomography, X-Ray Computed/methods [MeSH]
lokal Lung
lokal Radiographic Image Interpretation, Computer-Assisted [MeSH]
lokal Original Article
lokal Spectral shaping
lokal Infant [MeSH]
lokal Male [MeSH]
lokal Children
lokal Child [MeSH]
lokal Radiation Dosage [MeSH]
lokal Child, Preschool [MeSH]
lokal Dual-source computed tomography
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-9980-9528|https://frl.publisso.de/adhoc/uri/TWF5LCBNYXR0aGlhcyBTLg==|https://frl.publisso.de/adhoc/uri/V2Vpbm1hbm4sIERhbmllbA==|https://frl.publisso.de/adhoc/uri/SGFtbW9uLCBNYXR0aGlhcw==|https://frl.publisso.de/adhoc/uri/VHJldXRsZWluLCBDaHJpc3RvcGg=|https://frl.publisso.de/adhoc/uri/WmVpbGluZ2VyLCBNYXJ0aW4=|https://frl.publisso.de/adhoc/uri/S2llZmVyLCBBbGV4YW5kZXI=|https://frl.publisso.de/adhoc/uri/VHJvbGxtYW5uLCBSZWdpbmE=|https://frl.publisso.de/adhoc/uri/V29lbGZsZSwgSm9hY2hpbQ==|https://frl.publisso.de/adhoc/uri/VWRlciwgTWljaGFlbA==|https://frl.publisso.de/adhoc/uri/Um9tcGVsLCBPbGl2ZXI=
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1000 Erstellt am 2023-11-17T04:50:08.658+0100
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1000 Zuletzt bearbeitet 2023-12-01T05:09:34.867+0100
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