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1000 Titel
  • Recent findings in the genetics and epigenetics of asthma and allergy
1000 Autor/in
  1. Kabesch, Michael |
  2. Tost, Jörg |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-02-14
1000 Erschienen in
1000 Quellenangabe
  • 42(1):43-60
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00281-019-00777-w |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066293/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • In asthma and allergy genetics, a trend towards a few main topics developed over the last 2 years. First, a number of studies have been published recently which focus on overlapping and/or very specific phenotypes: within the allergy spectrum but also reaching beyond, looking for common genetic traits shared between different diseases or disease entities. Secondly, an urgently needed focus has been put on asthma and allergy genetics in populations genetically different from European ancestry. This acknowledges that the majority of new asthma patients today are not white and asthma is a truly worldwide disease. In epigenetics, recent years have seen several large-scale epigenome-wide association studies (EWAS) being published and a further focus was on the interaction between the environment and epigenetic signatures. And finally, the major trends in current asthma and allergy genetics and epigenetics comes from the field of pharmacogenetics, where it is necessary to understand the susceptibility for and mechanisms of current asthma and allergy therapies while at the same time, we need to have scientific answers to the recent availability of novel drugs that hold the promise for a more individualized therapy.
1000 Sacherschließung
lokal Adolescent [MeSH]
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Prospective Studies [MeSH]
lokal Interaction
lokal Allergy
lokal Asthma
lokal Cross-Sectional Studies [MeSH]
lokal Hypersensitivity/genetics [MeSH]
lokal Epigenesis, Genetic [MeSH]
lokal Asthma/genetics [MeSH]
lokal Genetics
lokal Epigenetics
lokal Review
lokal Child [MeSH]
lokal Child, Preschool [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/S2FiZXNjaCwgTWljaGFlbA==|https://frl.publisso.de/adhoc/uri/VG9zdCwgSsO2cmc=
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  1. Recent findings in the genetics and epigenetics of asthma and allergy
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1000 Erstellt am 2023-11-17T06:04:14.913+0100
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