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1000 Titel
  • The value of CT imaging and CRP quotient for detection of postbariatric complications
1000 Autor/in
  1. Duprée, Anna |
  2. de Heer, Jocelyn |
  3. Tichby, Michel |
  4. Ghadban, Tarik |
  5. Mann, Oliver |
  6. Grupp, K. |
  7. Pinnschmidt, Hans O. |
  8. Izbicki, Jakob R. |
  9. Wolter, Stefan |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-09-17
1000 Erschienen in
1000 Quellenangabe
  • 406(1):181-187
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00423-020-01986-w |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7870754/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!The diagnosis of major complications seems to be more challenging in obese patients. We aimed to show the relevance of routinely assessed clinical and paraclinical parameters as well as the relevance of CT scans in the diagnosis of major complications after bariatric procedures.!##!Methods!#!All patients who underwent operations (primary or revisional) in a 3-year period were retrospectively studied after bariatric surgery with a specific focus on the routinely assessed clinical parameters (tachycardia, temperature), paraclinical parameters on postoperative day (POD) 1 and 3 (C-reactive protein (CRP), leukocytes), and additional computed tomography (CT) scan results for the diagnosis of leakage, bleeding, intraabdominal abscess, superficial abscess, and other complications.!##!Results!#!A total of 587 patients were examined. In this cohort, 73 CT scans were performed due to suspected intraabdominal or pulmonary complication according to our hospital standard operating procedure. In total, 14 patients (2.4%) had a major complication (Clavien-Dindo grade IV/V). Of those, 10 patients (1.7%) had postoperative leakage. While the correct leakage diagnosis was only found in 33% of the patients by CT scan, the overall specificity of CT as a diagnostic tool for all kinds of complications remained high. Especially for abscess detection, CT scan showed a sensitivity and specificity of 100%. Multivariate analysis showed a significantly higher risk of leakage development characterized by a doubling of postoperative CRP level (odds ratio 4.84 (95% confidence interval 2.01-11.66, p < 0.001)). To simplify the use of CRP as a predictive factor for the diagnosis of leakage, a cut-off value of 2.4 was determined for the CRP quotient (POD3/POD1) with a sensitivity of 0.88 and a specificity of 0.89.!##!Conclusion!#!CT diagnostic after bariatric surgery has a high positive predictive value, especially for intraabdominal abscess formation. Nevertheless, CT scan for the diagnosis of leakage has a low sensitivity. Thus, a negative CT scan does not exclude the presence of a leakage. Using the described CRP quotient with a cut-off of 2.4, the risk of early leakage can be easily estimated. Furthermore, in any uncertain case of clinically suspected leakage, diagnostic laparoscopy should be performed.
1000 Sacherschließung
lokal Original Article
lokal Tomography, X-Ray Computed [MeSH]
lokal Complications
lokal Bariatric surgery
lokal Laparoscopy [MeSH]
lokal CRP quotient
lokal Humans [MeSH]
lokal C-Reactive Protein/analysis [MeSH]
lokal Bariatric Surgery/adverse effects [MeSH]
lokal Retrospective Studies [MeSH]
lokal CT scan
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0003-3323-122X|https://frl.publisso.de/adhoc/uri/ZGUgSGVlciwgSm9jZWx5bg==|https://frl.publisso.de/adhoc/uri/VGljaGJ5LCBNaWNoZWw=|https://frl.publisso.de/adhoc/uri/R2hhZGJhbiwgVGFyaWs=|https://frl.publisso.de/adhoc/uri/TWFubiwgT2xpdmVy|https://frl.publisso.de/adhoc/uri/R3J1cHAsIEsu|https://frl.publisso.de/adhoc/uri/UGlubnNjaG1pZHQsIEhhbnMgTy4=|https://frl.publisso.de/adhoc/uri/SXpiaWNraSwgSmFrb2IgUi4=|https://frl.publisso.de/adhoc/uri/V29sdGVyLCBTdGVmYW4=
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1000 Erstellt am 2023-11-17T08:49:32.759+0100
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