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1000 Titel
  • Probabilistic tractography in the ventrolateral thalamic nucleus: cerebellar and pallidal connections
1000 Autor/in
  1. Pelzer, Esther A. |
  2. Pauls, K. Amande M. |
  3. Braun, Nina |
  4. Tittgemeyer, Marc |
  5. Timmermann, Lars |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-05-03
1000 Erschienen in
1000 Quellenangabe
  • 225(5):1685-1689
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00429-020-02076-9 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7286851/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • The ventrolateral thalamic nucleus (VL), as part of the 'motor thalamus', is main relay station of cerebellar and pallidal projections. It comprises anterior (VLa) and posterior (VLpd and VLpv) subnuclei. Though the fibre architecture of cerebellar and pallidal projections to of the VL nucleus has already been focus in a numerous amount of in vitro studies mainly in animals, probabilistic tractography now offers the possibility of an in vivo comparison in healthy humans. In this study we performed a (a) qualitative and (b) quantitative examination of VL-cerebellar and VL-pallidal pathways and compared the probability distributions between both projection fields in the VL after an (I) atlas-based and (II) manual-based segmentation procedure. Both procedures led to high congruent results of cerebellar and pallidal connectivity distributions: the maximum of pallidal projections was located in anterior and medial parts of the VL nucleus, whereas cerebellar connectivity was more located in lateral and posterior parts. The median connectivity for cerebellar connections in both approaches (manual and atlas-based segmentation) was VLa > VLpv > VLpd, whereas the pallidal median connectivity was VLa ~ VLpv > VLpd in the atlas-based approach and VLpv > VLa > VLpd in the manual approach.
1000 Sacherschließung
lokal Basal ganglia
lokal Female [MeSH]
lokal Adult [MeSH]
lokal Neural Pathways/anatomy
lokal Humans [MeSH]
lokal Ventral Thalamic Nuclei/anatomy
lokal Diffusion Tensor Imaging/methods [MeSH]
lokal Ventrolateral thalamus
lokal Globus Pallidus/anatomy
lokal Male [MeSH]
lokal Probabilistic tractography
lokal Young Adult [MeSH]
lokal Brain Mapping/methods [MeSH]
lokal Qualitative and quantitative analyses
lokal Cerebellum
lokal Cerebellum/anatomy
lokal Short Communication
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/UGVsemVyLCBFc3RoZXIgQS4=|https://frl.publisso.de/adhoc/uri/UGF1bHMsIEsuIEFtYW5kZSBNLg==|https://frl.publisso.de/adhoc/uri/QnJhdW4sIE5pbmE=|https://frl.publisso.de/adhoc/uri/VGl0dGdlbWV5ZXIsIE1hcmM=|https://frl.publisso.de/adhoc/uri/VGltbWVybWFubiwgTGFycw==
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1000 Erstellt am 2023-11-17T09:35:21.496+0100
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