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1000 Titel
  • Tendon elongation with bovine pericardium in strabismus surgery—indications beyond Graves’ orbitopathy
1000 Autor/in
  1. Hedergott, Andrea |
  2. Pink-Theofylaktopoulos, Ursula |
  3. Neugebauer, Antje |
  4. Fricke, Julia |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-09-19
1000 Erschienen in
1000 Quellenangabe
  • 259(1):145-155
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00417-020-04939-7 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7790785/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!For some patients with complex ocular motility disorders, conventional strabismus surgery is insufficient. Surgery with tendon elongation allows correction of larger angles and maintains a sufficient arc of contact for rectus muscles. This study reports results for tendon elongation with bovine pericardium (Tutopatch®) in indications other than Graves' orbitopathy in which it is already widely used.!##!Methods!#!We reviewed the records of all patients who underwent surgery with Tutopatch® in our institution. Angles of squint and head postures were analyzed preoperatively, on the first postoperative day, and in the long term (median 9 weeks after the operation). Patients with Graves' orbitopathy were excluded.!##!Results!#!From 2011 to 2018, the procedures on 58 eyes of 54 patients (35 females, median age 35 years (3-75)) met the inclusion criteria. Horizontal rectus muscle surgery (53 eyes) was conducted on patients with residual strabismus (13), Duane's retraction syndrome with eso- (type I: 16)/exodeviation (type II: 2, type III: 1), 6th (7)/3rd nerve palsy (7), Möbius syndrome (2), congenital fibrosis of the extraocular muscles type 3A (CFEOM3A, TUBB3 mutation) (4), and orbital apex syndrome (1). Vertical rectus muscle surgery (5 eyes) was conducted on patients with myasthenia (1), vertical tropia after orbital floor fracture (1), CFEOM1 (2), and Parry-Romberg syndrome (1). 42 eyes had prior eye muscle surgery (1-5 procedures, median 1). Out of 45 patients with postoperative long-term data, 43 showed an angle reduction. Fifty-one percent had an angle of 10Δ (prism diopter) or less, one had a significant over-effect, and 10 had revision surgery. For the heterogeneous group of residual eso- and exotropias, the median absolute horizontal angle was reduced from 35Δ (16 to 45Δ) to 9Δ (0 to 40Δ), for Duane's retraction syndrome from 27.5Δ (9 to 40Δ) to 7Δ (0 to 40Δ), and for sixth and third nerve palsies from 43Δ (20 to 75Δ) to 18Δ (4 to 40Δ). For 3 patients with vertical rectus muscle surgery, the median absolute vertical angle was reduced from 30Δ (20 to 45Δ) to 4Δ (1 to 22Δ). The motility range was shifted in the direction contrary to the elongated muscle in all subgroups. A considerable reduction of the excursion into the field of action of the elongated muscle had to be registered.!##!Conclusions!#!Strabismus surgery with bovine pericardium introduces new surgical options for complicated revisions and for rare and complex oculomotor dysfunctions. Yet, it has to be recognized that this type of surgery aiming at maximum effects, despite preservation or restitution of the arc of contact, leads to reduction of the excursion into the field of action of the elongated muscle. Furthermore, dose finding can be difficult depending on the underlying pathology and more than one intervention might be necessary for optimal results.
1000 Sacherschließung
lokal Female [MeSH]
lokal Ophthalmologic Surgical Procedures [MeSH]
lokal Strabismus/surgery [MeSH]
lokal Adult [MeSH]
lokal Graves Ophthalmopathy/diagnosis [MeSH]
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Strabismus surgery
lokal Bovine pericardium
lokal Retrospective Studies [MeSH]
lokal Tendon elongation
lokal Animals [MeSH]
lokal Strabismus/etiology [MeSH]
lokal Tutopatch®
lokal Pericardium/surgery [MeSH]
lokal Tendons [MeSH]
lokal Graves Ophthalmopathy/surgery [MeSH]
lokal Oculomotor Muscles/surgery [MeSH]
lokal Cattle [MeSH]
lokal Neurophthalmology
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-6398-3919|https://frl.publisso.de/adhoc/uri/UGluay1UaGVvZnlsYWt0b3BvdWxvcywgVXJzdWxh|https://frl.publisso.de/adhoc/uri/TmV1Z2ViYXVlciwgQW50amU=|https://frl.publisso.de/adhoc/uri/RnJpY2tlLCBKdWxpYQ==
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