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1000 Titel
  • Adhesion and whitening effects of P11-4 self-assembling peptide and HAP suspension on bovine enamel
1000 Autor/in
  1. Hojabri, Niloofar |
  2. Kaisarly, Dalia |
  3. Kunzelmann, Karl-Heinz |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-10-27
1000 Erschienen in
1000 Quellenangabe
  • 25(5):3237-3247
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00784-020-03654-1 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8060195/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Objectives!#!This study evaluated the adhesion and whitening effects of a combination of P11-4 self-assembling peptide and hydroxyapatite (peptide-HAP) on bovine enamel.!##!Methods!#!Forty-six caries-free bovine teeth were selected, and 40 teeth were randomly allocated to one of five groups (n = 8). First, the effects of application frequency, exposure time, and storage in saliva on the whitening effects of an experimental low-concentrated peptide-HAP suspension (0.5 wt% HAP; Curodont, Credentis) were evaluated and compared with a commercial bleaching agent (VivaStyle Paint on Plus, VS, Ivoclar Vivadent). Tooth color was measured using a spectrophotometer (Gretag MacBeth), and color changes ΔE were statistically analyzed. Second, the effects of peptide-HAP concentration (low versus high: 6.25% HAP; Curodont Protect), and its interactions with saliva and postapplication restaining, were investigated. Third, enamel surfaces (n = 2) were treated with low concentration peptide-HAP and high-concentration peptide-HAP in polymeric and monomeric forms (Curodont Protect & Curodont Repair, Credentis) and analyzed by SEM.!##!Results!#!The ΔE of the low-concentration peptide-HAP suspension did not differ from that of VS. Application frequency, exposure time, and storage in saliva did not have any significant impact on whitening efficacy of the peptide-HAP suspension. Increasing the concentration of the suspension did not promote overall ΔE. SEM observations confirmed the presence of the newly generated peptide and HAP on the enamel surface.!##!Conclusions!#!The peptide-HAP suspension is a mild tooth whitener, and the adhesion of peptide-HAP to enamel is concentration dependent.!##!Clinical relevance!#!This peptide-HAP suspension is effective in offsetting discoloration caused by restaining after treatment.
1000 Sacherschließung
lokal Whitening effects
lokal Durapatite [MeSH]
lokal Dental Enamel [MeSH]
lokal Animals [MeSH]
lokal Color measurement
lokal SEM
lokal Original Article
lokal Bovine enamel
lokal Tooth [MeSH]
lokal Self-assembling peptide P11-4
lokal Peptides/pharmacology [MeSH]
lokal Cattle [MeSH]
lokal Hydroxyapatite (HAP)
lokal Color [MeSH]
lokal Tooth Bleaching [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/SG9qYWJyaSwgTmlsb29mYXI=|https://orcid.org/0000-0003-1520-2062|https://frl.publisso.de/adhoc/uri/S3VuemVsbWFubiwgS2FybC1IZWlueg==
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1000 Erstellt am 2023-11-17T13:27:44.966+0100
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1000 Zuletzt bearbeitet Fri Dec 01 07:07:52 CET 2023
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