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1000 Titel
  • Surgical treatment of aggressive pituitary adenomas and pituitary carcinomas
1000 Autor/in
  1. Buchfelder, Michael |
  2. Schlaffer, Sven-Martin |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-06-04
1000 Erschienen in
1000 Quellenangabe
  • 21(2):253-261
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s11154-020-09563-8 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7303081/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Surgery of aggressive pituitary adenomas and pituitary carcinomas is part of the interdisciplinary management of these difficult to treat tumors. Invasion, giant size and unusual, asymmetric extent of these tumors frequently require modifications or extensions of the standard approaches for transsphenoidal and transcranial surgery. Frequently, only debulking procedures can be performed. In aggressive and hormone secreting adenomas, the remission rates achieved by surgery alone are relatively poor and adjuvant medical treatments or irradiation are needed. Safe resection of as much tumor as possible and symptomatic control is aimed at, rather than remission. Many procedures are required for rapid progression of lesions or recurrences, in order to extend the survival of the patients. Metastases of pituitary carcinomas within the cranial cavity or spine can be attacked. Since they can occur anywhere in the brain or spinal canal they require the entire battery of neurosurgical approaches. Unfortunately, in this group of pituitary tumors, the complication rates are higher than in primary operations of enclosed adenomas. The respective techniques with their facilities and limitations are reviewed in this article.
1000 Sacherschließung
lokal Humans [MeSH]
lokal Pituitary carcinomas
lokal Interdisciplinary management
lokal Pituitary Neoplasms/pathology [MeSH]
lokal Adenoma/surgery [MeSH]
lokal Transsphenoidal surgery
lokal Neoplasm Invasiveness/pathology [MeSH]
lokal Cavernous sinus
lokal Invasive adenoma
lokal Pituitary Neoplasms/surgery [MeSH]
lokal Carcinoma/pathology [MeSH]
lokal Article
lokal Transcranial surgery
lokal Aggressive growth
lokal Carcinoma/surgery [MeSH]
lokal Adenoma/pathology [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/QnVjaGZlbGRlciwgTWljaGFlbA==|https://orcid.org/0000-0002-6351-1137
1000 Hinweis
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1000 Erstellt am 2023-11-17T17:10:35.514+0100
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1000 Zuletzt bearbeitet Fri Dec 01 08:06:43 CET 2023
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