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1000 Titel
  • Tibiopedal and distal femoral retrograde vascular access for challenging chronic total occlusions: predictors for technical success, and complication rates in a large single-center cohort
1000 Autor/in
  1. Grözinger, Gerd |
  2. Hallecker, Jan |
  3. Grosse, Ulrich |
  4. Syha, Roland |
  5. Ketelsen, Dominik |
  6. Brechtel, Klaus |
  7. Lescan, Mario |
  8. Nikolaou, Konstantin |
  9. Artzner, Christoph |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-07-28
1000 Erschienen in
1000 Quellenangabe
  • 31(1):535-542
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00330-020-07082-3 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7755625/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Objective!#!To evaluate the safety and effectiveness of tibiopedal and distal femoral access for retrograde crossing of chronic total occlusion (CTO) in Rutherford stage III to VI peripheral arterial occlusive disease, and to determine factors that correlate with technical success.!##!Material and methods!#!One hundred seventy-one consecutive patients were included in this retrospective study. Rutherford stages were III, IV, and V/VI in 24%, 8%, and 67% of patients. Inclusion criteria were CTO at the superficial femoral (SFA), popliteal (PA), and/or below-the-knee (BTK) level, and a failed antegrade treatment followed by a distal retrograde approach. The numbers of occluded vascular levels (OVL), lesion length, degree of calcification, technical success rate, complications, and clinical outcome were noted.!##!Results!#!OVL were 1 in 72%, 2 in 20%, and 3 in 8% of patients. CTOs were longer than 20 cm in 45.6% of cases and showed severe calcifications in 50.3%. Target vessels for distal access were the distal SFA/PA in 17% and BTK in 83%. The overall technical success rate was 82%. Severe calcification decreased technical success (p = 0.01) despite lesion length and Rutherford stage. Clinical outcome improved in 123/152 patients with a significant increase of the median ABI (N = 158) from 0.53 (interquartile range 0.39 to 0.61) to 0.85 (0.59 to 1.03; p < 0.001). Complications were reported in 7.6% cases with 2.3% related to the distal vascular access.!##!Conclusion!#!The tibiopedal and distal femoral retrograde access presents a safe and effective treatment option of CTOs at the thigh and/or BTK after a failed antegrade attempt improving clinical outcome. Technical success decreased with lesion's degree of calcification.!##!Key points!#!• Safety and effectiveness of the tibiopedal and distal femoral access for retrograde crossing of chronic total occlusion. • Target lesion's degree of calcification decreases technical success. • Complications related to the distal vascular access were rare.
1000 Sacherschließung
lokal Peripheral arterial diseases
lokal Chronic Disease [MeSH]
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Peripheral Arterial Disease/diagnostic imaging [MeSH]
lokal Retrospective Studies [MeSH]
lokal Angioplasty
lokal Arterial occlusive diseases
lokal Arteriosclerosis
lokal Femoral Artery/diagnostic imaging [MeSH]
lokal Interventional
lokal Cohort Studies [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/R3LDtnppbmdlciwgR2VyZA==|https://frl.publisso.de/adhoc/uri/SGFsbGVja2VyLCBKYW4=|https://frl.publisso.de/adhoc/uri/R3Jvc3NlLCBVbHJpY2g=|https://frl.publisso.de/adhoc/uri/U3loYSwgUm9sYW5k|https://frl.publisso.de/adhoc/uri/S2V0ZWxzZW4sIERvbWluaWs=|https://frl.publisso.de/adhoc/uri/QnJlY2h0ZWwsIEtsYXVz|https://frl.publisso.de/adhoc/uri/TGVzY2FuLCBNYXJpbw==|https://frl.publisso.de/adhoc/uri/Tmlrb2xhb3UsIEtvbnN0YW50aW4=|https://frl.publisso.de/adhoc/uri/QXJ0em5lciwgQ2hyaXN0b3Bo
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1000 Erstellt am 2023-11-17T21:21:49.521+0100
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