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1000 Titel
  • Low-dose MDCT: evaluation of the impact of systematic tube current reduction and sparse sampling on the detection of degenerative spine diseases
1000 Autor/in
  1. Sollmann, Nico |
  2. Mei, Kai |
  3. Riederer, Isabelle |
  4. Probst, Monika |
  5. Löffler, Maximilian T. |
  6. Kirschke, Jan S. |
  7. Noël, Peter B. |
  8. Baum, Thomas |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-09-18
1000 Erschienen in
1000 Quellenangabe
  • 31(4):2590-2600
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00330-020-07278-7 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7979597/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Objectives!#!To investigate potential radiation dose reduction for multi-detector computed tomography (MDCT) exams of the spine by using sparse sampling and virtually lowered tube currents combined with statistical iterative reconstruction (SIR).!##!Methods!#!MDCT data of 26 patients (68.9 ± 11.7 years, 42.3% males) were retrospectively simulated as if the scans were acquired at 50%, 10%, 5%, and 3% of the original X-ray tube current or number of projections, using SIR for image reconstructions. Two readers performed qualitative image evaluation considering overall image quality, artifacts, and contrast and determined the number and type of degenerative changes. Scoring was compared between readers and virtual low-dose and sparse-sampled MDCT, respectively.!##!Results!#!Image quality and contrast decreased with virtual lowering of tube current and sparse sampling, but all degenerative changes were correctly detected in MDCT with 50% of tube current as well as MDCT with 50% of projections. Sparse-sampled MDCT with only 10% of initial projections still enabled correct identification of all degenerative changes, in contrast to MDCT with virtual tube current reduction by 90% where non-calcified disc herniations were frequently missed (R1: 23.1%, R2: 21.2% non-diagnosed herniations). The average volumetric CT dose index (CTDI!##!Conclusions!#!MDCT with 50% of original tube current or projections using SIR still allowed for accurate diagnosis of degenerative changes. Sparse sampling may be more promising for further radiation dose reductions since no degenerative changes were missed with 10% of initial projections.!##!Key points!#!• Most common degenerative changes of the spine can be diagnosed in multi-detector CT with 50% of tube current or number of projections. • Sparse-sampled multi-detector CT with only 10% of initial projections still enables correct identification of degenerative changes, in contrast to imaging with 10% of original tube current. • Sparse sampling may be a promising option for distinct lowering of radiation dose, reducing the CTDI
1000 Sacherschließung
lokal Musculoskeletal
lokal Female [MeSH]
lokal Humans [MeSH]
lokal Radiation dosage
lokal Retrospective Studies [MeSH]
lokal Artifacts [MeSH]
lokal Intervertebral disc disease
lokal Radiographic Image Interpretation, Computer-Assisted [MeSH]
lokal Artifacts
lokal Male [MeSH]
lokal Multidetector Computed Tomography [MeSH]
lokal Intervertebral disc degeneration
lokal Radiation Dosage [MeSH]
lokal Spine [MeSH]
lokal Image processing, computer-assisted
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-8120-2223|https://frl.publisso.de/adhoc/uri/TWVpLCBLYWk=|https://frl.publisso.de/adhoc/uri/UmllZGVyZXIsIElzYWJlbGxl|https://frl.publisso.de/adhoc/uri/UHJvYnN0LCBNb25pa2E=|https://frl.publisso.de/adhoc/uri/TMO2ZmZsZXIsIE1heGltaWxpYW4gVC4=|https://frl.publisso.de/adhoc/uri/S2lyc2Noa2UsIEphbiBTLg==|https://frl.publisso.de/adhoc/uri/Tm-Dq2wsIFBldGVyIEIu|https://frl.publisso.de/adhoc/uri/QmF1bSwgVGhvbWFz
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1000 Erstellt am 2023-11-17T21:42:51.456+0100
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1000 Zuletzt bearbeitet Fri Dec 01 09:35:22 CET 2023
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