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1000 Titel
  • Clinical, procedural and long-term outcome of ischemic VT ablation in patients with previous anterior versus inferior myocardial infarction
1000 Autor/in
  1. Wasmer, Kristina |
  2. Reinecke, Holger |
  3. Heitmann, Marius |
  4. Dechering, Dirk G. |
  5. Reinke, Florian |
  6. Lange, Philipp S. |
  7. Frommeyer, Gerrit |
  8. Kochhäuser, Simon |
  9. Leitz, Patrick |
  10. Eckardt, Lars |
  11. Köbe, Julia |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-03-10
1000 Erschienen in
1000 Quellenangabe
  • 109(10):1282-1291
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00392-020-01622-z |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7515937/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Outcome of ischemic VT ablation may differ between patients with previous myocardial infarction (MI) in relation to infarct localization.!##!Methods!#!We analyzed procedural data, acute and long-term outcomes of 152 consecutive patients (139 men, mean age 67 ± 9 years) with previous anterior or inferior MI who underwent ischemic VT ablation at our institution between January 2010 and October 2015.!##!Results!#!More patients had a history of inferior MI (58%). Mean ejection fraction was significantly lower in anterior MI patients (28 ± 10% vs. 34 ± 10%, p < 0.001). NYHA class and presence of comorbidities were not different between the groups. Indication for the procedure was electrical storm in 43% of patients, and frequent implantable cardioverter defibrillator (ICD) therapies in 57%, and did not differ significantly between anterior and inferior MI patients. A mean of 3 ± 2 VT morphologies were inducible, with a trend towards more VT in the anterior MI group (3.1 ± 2.2 vs. 2.6 ± 1.9, p = 0.18). Procedural parameters and acute success did not differ between the groups. During a mean follow-up of 3 ± 2 years, more anterior MI patients had undergone a re-ablation (49% vs. 33%, p = 0.09, Chi-square test). There was a trend towards more ICD shocks in patients with previous anterior MI (46% vs. 34%). After adjusting for risk factors and ejection fraction, multivariable Cox regression analyses showed no significant difference in mortality (p = 0.78) and cardiovascular mortality between infarct localizations (p = 0.6).!##!Conclusion!#!Clinical characteristics of patients with anterior and inferior MI are similar except for ejection fraction. Patients with inferior MI appear to have better outcome regarding survival, ICD shocks and re-ablation, but this appears to be related to better ejection fraction when compared with anterior MI.
1000 Sacherschließung
lokal Anterior Wall Myocardial Infarction/complications [MeSH]
lokal Female [MeSH]
lokal Follow-Up Studies [MeSH]
lokal Ischemic cardiomyopathy
lokal Aged, 80 and over [MeSH]
lokal Localization of scar
lokal Aged [MeSH]
lokal Adult [MeSH]
lokal Inferior Wall Myocardial Infarction/complications [MeSH]
lokal Humans [MeSH]
lokal Tachycardia, Ventricular/surgery [MeSH]
lokal Treatment Outcome [MeSH]
lokal Catheter ablation
lokal Retrospective Studies [MeSH]
lokal Catheter Ablation/methods [MeSH]
lokal Defibrillators, Implantable/adverse effects [MeSH]
lokal Middle Aged [MeSH]
lokal Stroke Volume/physiology [MeSH]
lokal Male [MeSH]
lokal Original Paper
lokal Ventricular tachycardia
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/V2FzbWVyLCBLcmlzdGluYQ==|https://frl.publisso.de/adhoc/uri/UmVpbmVja2UsIEhvbGdlcg==|https://frl.publisso.de/adhoc/uri/SGVpdG1hbm4sIE1hcml1cw==|https://frl.publisso.de/adhoc/uri/RGVjaGVyaW5nLCBEaXJrIEcu|https://frl.publisso.de/adhoc/uri/UmVpbmtlLCBGbG9yaWFu|https://frl.publisso.de/adhoc/uri/TGFuZ2UsIFBoaWxpcHAgUy4=|https://frl.publisso.de/adhoc/uri/RnJvbW1leWVyLCBHZXJyaXQ=|https://frl.publisso.de/adhoc/uri/S29jaGjDpHVzZXIsIFNpbW9u|https://frl.publisso.de/adhoc/uri/TGVpdHosIFBhdHJpY2s=|https://frl.publisso.de/adhoc/uri/RWNrYXJkdCwgTGFycw==|https://frl.publisso.de/adhoc/uri/S8O2YmUsIEp1bGlh
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