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1000 Titel
  • Left atrial appendage closure in patients with chronic kidney disease: results from the German multicentre LAARGE registry
1000 Autor/in
  1. Fastner, Christian |
  2. Brachmann, Johannes |
  3. Lewalter, Thorsten |
  4. Zeymer, Uwe |
  5. Sievert, Horst |
  6. Borggrefe, Martin |
  7. Nienaber, Christoph A. |
  8. WeiĂź, Christian |
  9. Pleger, Sven T. |
  10. Ince, HĂĽseyin |
  11. Maier, Jens |
  12. Achenbach, Stephan |
  13. Sigusch, Holger H. |
  14. Hochadel, Matthias |
  15. Schneider, Steffen |
  16. Senges, Jochen |
  17. Akin, Ibrahim |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-04-15
1000 Erschienen in
1000 Quellenangabe
  • 110(1):12-20
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00392-020-01638-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7806558/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Objectives!#!Chronic kidney disease (CKD) is associated with an increased complication rate after cardiac interventions. Although CKD has a high prevalence among atrial fibrillation patients, the impact of CKD on periprocedural complications and the outcome after an interventional left atrial appendage closure (LAAC) is unclear. The present study, therefore, aimed to investigate whether CKD influences the procedure's effectiveness and safety.!##!Methods!#!LAARGE is a prospective, non-randomised registry. LAAC was conducted with different standard commercial devices, and the follow-up period was one year. CKD was defined by an eGFR < 60 mL/min/1.73 m!##!Results!#!Two hundred ninety-nine of 623 patients (48.0%) revealed a CKD. The prevalence of cardiovascular comorbidity, CHA!##!Conclusions!#!Despite an increased cardiovascular risk profile of CKD patients, device implantation was safe, and LAAC was associated with effective stroke prevention across all CKD stages.
1000 SacherschlieĂźung
lokal Glomerular Filtration Rate/physiology [MeSH]
lokal Female [MeSH]
lokal Renal Insufficiency, Chronic/physiopathology [MeSH]
lokal Atrial Appendage/surgery [MeSH]
lokal Follow-Up Studies [MeSH]
lokal Aged, 80 and over [MeSH]
lokal Aged [MeSH]
lokal Atrial Fibrillation/complications [MeSH]
lokal Humans [MeSH]
lokal Prospective Studies [MeSH]
lokal Treatment Outcome [MeSH]
lokal Atrial fibrillation
lokal Renal Insufficiency, Chronic/complications [MeSH]
lokal LAARGE
lokal Cardiac Surgical Procedures/methods [MeSH]
lokal Atrial Fibrillation/surgery [MeSH]
lokal Male [MeSH]
lokal Left atrial appendage closure
lokal Germany [MeSH]
lokal Original Paper
lokal Chronic kidney disease
lokal Septal Occluder Device [MeSH]
lokal Left atrial appendage
lokal Registries [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/RmFzdG5lciwgQ2hyaXN0aWFu|https://frl.publisso.de/adhoc/uri/QnJhY2htYW5uLCBKb2hhbm5lcw==|https://frl.publisso.de/adhoc/uri/TGV3YWx0ZXIsIFRob3JzdGVu|https://frl.publisso.de/adhoc/uri/WmV5bWVyLCBVd2U=|https://frl.publisso.de/adhoc/uri/U2lldmVydCwgSG9yc3Q=|https://frl.publisso.de/adhoc/uri/Qm9yZ2dyZWZlLCBNYXJ0aW4=|https://frl.publisso.de/adhoc/uri/TmllbmFiZXIsIENocmlzdG9waCBBLg==|https://frl.publisso.de/adhoc/uri/V2Vpw58sIENocmlzdGlhbg==|https://frl.publisso.de/adhoc/uri/UGxlZ2VyLCBTdmVuIFQu|https://frl.publisso.de/adhoc/uri/SW5jZSwgSMO8c2V5aW4=|https://frl.publisso.de/adhoc/uri/TWFpZXIsIEplbnM=|https://frl.publisso.de/adhoc/uri/QWNoZW5iYWNoLCBTdGVwaGFu|https://frl.publisso.de/adhoc/uri/U2lndXNjaCwgSG9sZ2VyIEgu|https://frl.publisso.de/adhoc/uri/SG9jaGFkZWwsIE1hdHRoaWFz|https://frl.publisso.de/adhoc/uri/U2NobmVpZGVyLCBTdGVmZmVu|https://frl.publisso.de/adhoc/uri/U2VuZ2VzLCBKb2NoZW4=|https://frl.publisso.de/adhoc/uri/QWtpbiwgSWJyYWhpbQ==
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1000 Erstellt am 2023-11-18T02:20:55.873+0100
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