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1000 Titel
  • Impact of the introduction of percutaneous edge-to-edge mitral valve reconstruction on clinical practice in Germany compared to surgical valve repair
1000 Autor/in
  1. Frankenstein, Lutz |
  2. Kaier, Klaus |
  3. Katus, Hugo A. |
  4. Bode, Christoph |
  5. Wengenmayer, Tobias |
  6. von zur Mühlen, Constantin |
  7. Bekeredjian, Raffi |
  8. Täger, Tobias |
  9. Zehender, Manfred |
  10. Fröhlich, Hanna |
  11. Stachon, Peter |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-05-27
1000 Erschienen in
1000 Quellenangabe
  • 110(5):620-627
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00392-020-01675-0 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8099833/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!The introduction of percutaneous mitral valve (MV) repair had an effect on clinical practice in comparison with surgical MV repair. Complete nationwide data are useful in examining how the introduction of a new technique influences clinical practice.!##!Methods!#!We analyzed procedural numbers, patient characteristics, and in-hospital outcomes for all percutaneous edge-to-edge and surgical MV reconstruction procedures performed in Germany between 2009 and 2015.!##!Results!#!12,664 percutaneous edge-to-edge and 22,825 surgical MV reconstructions were recorded. Numbers increased steadily, albeit more rapidly in the percutaneous edge-to-edge group (108-4079 vs. 2923-3603 with surgical MV reconstruction). Patients with percutaneous edge-to-edge MV reconstruction were older (75.6 ± 8.8 vs 61.6 ± 13.4 years, P < 0.001) and at higher operative risk (estimated logistic EuroSCORE 13.2% vs. 4.7%, P < 0.001) compared to those undergoing surgery. However, in-hospital mortality did not differ (2.9% vs. 2.8%; P = 0.395). This was also true for the subset of 2103 patients at intermediate operative risk as defined by a logistic EuroSCORE ≥ 4% and ≤ 9%. Of note, complication rates (except acute kidney injury) were more favorable in patients undergoing percutaneous edge-to-edge reconstruction.!##!Conclusions!#!Percutaneous edge-to-edge MV reconstruction has markedly changed clinical practice of MR therapy in Germany. Annual overall procedural numbers more than doubled, with a massive increase in percutaneous edge-to-edge procedures. Our data demonstrate its use mainly in high-risk patients and prove the favorable safety profile of this novel technique, with low in-hospital mortality and complication rates.
1000 Sacherschließung
lokal Female [MeSH]
lokal Age Factors [MeSH]
lokal Aged, 80 and over [MeSH]
lokal Aged [MeSH]
lokal Mitral Valve Insufficiency/surgery [MeSH]
lokal Humans [MeSH]
lokal Surgical valve repair
lokal Treatment Outcome [MeSH]
lokal Cardiac Catheterization/methods [MeSH]
lokal Postoperative Complications/epidemiology [MeSH]
lokal Middle Aged [MeSH]
lokal Risk Factors [MeSH]
lokal MitraClip
lokal Percutaneous mitral valve repair
lokal Hospital Mortality [MeSH]
lokal Male [MeSH]
lokal Germany [MeSH]
lokal Original Paper
lokal Mitral Valve/surgery [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-7216-1004|https://frl.publisso.de/adhoc/uri/S2FpZXIsIEtsYXVz|https://frl.publisso.de/adhoc/uri/S2F0dXMsIEh1Z28gQS4=|https://frl.publisso.de/adhoc/uri/Qm9kZSwgQ2hyaXN0b3Bo|https://frl.publisso.de/adhoc/uri/V2VuZ2VubWF5ZXIsIFRvYmlhcw==|https://frl.publisso.de/adhoc/uri/dm9uIHp1ciBNw7xobGVuLCBDb25zdGFudGlu|https://frl.publisso.de/adhoc/uri/QmVrZXJlZGppYW4sIFJhZmZp|https://frl.publisso.de/adhoc/uri/VMOkZ2VyLCBUb2JpYXM=|https://frl.publisso.de/adhoc/uri/WmVoZW5kZXIsIE1hbmZyZWQ=|https://frl.publisso.de/adhoc/uri/RnLDtmhsaWNoLCBIYW5uYQ==|https://frl.publisso.de/adhoc/uri/U3RhY2hvbiwgUGV0ZXI=
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1000 Erstellt am 2023-11-18T02:29:52.117+0100
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