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1000 Titel
  • Pain severity and analgesics use in the community-dwelling older population: a drug utilization study from Germany
1000 Autor/in
  1. Nguyen, Thi Ngoc Mai |
  2. Laetsch, Dana Clarissa |
  3. Chen, Li-Ju |
  4. Haefeli, Walter Emil |
  5. Meid, Andreas D |
  6. Brenner, Hermann |
  7. Schöttker, Ben |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-07-10
1000 Erschienen in
1000 Quellenangabe
  • 76(12):1695-1707
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00228-020-02954-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7661425/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!Chronic pain is common in the older population and a significant public health concern. However, comprehensive studies on analgesics use in this age group from Germany are scarce. This study aims to give a comprehensive overview on the use of the most common therapeutic groups of analgesics in community-dwelling older adults from Germany.!##!Methods!#!A cross-sectional study was carried out using data from a German cohort of 2038 community-dwelling adults aged 63-89 years. Descriptive statistics and logistic regression models were applied to assess the utilization of analgesics by age, sex, pain severity, pain duration, and locations.!##!Results!#!One out of four study participants was suffering from high-intensity or disabling pain. Approximately half of those taking analgesics still reported to suffer from high-intensity or disabling pain. Among analgesics users, occasional non-steroidal anti-inflammatory drugs (NSAIDs) use was the most frequent pain therapy (in 43.6% of users), followed by metamizole (dipyrone) use (16.1%), regular NSAIDs use (12.9%), strong opioids use (12.7%), and weak opioids use (12.0%). In multivariate logistic regression models, higher age, higher pain severity, longer pain duration, abdominal pain, and back pain were statistically significantly associated with opioids use. Metamizole use was also statistically significantly associated with higher pain severity but inversely associated with pain duration.!##!Conclusions!#!A significant number of older German adults are affected by high-intensity and disabling chronic pain despite receiving analgesics. Long-term studies are needed to compare the effectiveness and safety of different treatments for chronic pain in older adults.
1000 Sacherschließung
lokal Aged, 80 and over [MeSH]
lokal Aged [MeSH]
lokal Surveys and Questionnaires/statistics
lokal Analgesics
lokal Germany/epidemiology [MeSH]
lokal Dipyrone/therapeutic use [MeSH]
lokal Analgesics, Opioid/therapeutic use [MeSH]
lokal Chronic Pain/diagnosis [MeSH]
lokal Chronic Pain/epidemiology [MeSH]
lokal Male [MeSH]
lokal Drug Utilization/statistics
lokal Independent Living/statistics
lokal Prevalence [MeSH]
lokal Female [MeSH]
lokal Anti-Inflammatory Agents, Non-Steroidal/therapeutic use [MeSH]
lokal Follow-Up Studies [MeSH]
lokal Older adult
lokal Humans [MeSH]
lokal Severity of Illness Index [MeSH]
lokal Treatment Outcome [MeSH]
lokal Drug utilization study
lokal NSAIDs
lokal Chronic Pain/drug therapy [MeSH]
lokal Opioids
lokal Middle Aged [MeSH]
lokal Cross-Sectional Studies [MeSH]
lokal Pain Measurement/statistics
lokal Metamizole
lokal Pharmacoepidemiology and Prescription
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/Tmd1eWVuLCBUaGkgTmdvYyBNYWk=|https://frl.publisso.de/adhoc/uri/TGFldHNjaCwgRGFuYSBDbGFyaXNzYQ==|https://frl.publisso.de/adhoc/uri/Q2hlbiwgTGktSnU=|https://frl.publisso.de/adhoc/uri/SGFlZmVsaSwgV2FsdGVyIEVtaWw=|https://frl.publisso.de/adhoc/uri/TWVpZCwgQW5kcmVhcyBE|https://frl.publisso.de/adhoc/uri/QnJlbm5lciwgSGVybWFubg==|https://orcid.org/0000-0002-1217-4521
1000 Hinweis
  • DeepGreen-ID: 5d2925ad8dfc42a48645670b7d28740d ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 @id frl:6470180.rdf
1000 Erstellt am 2023-11-18T04:26:53.378+0100
1000 Erstellt von 322
1000 beschreibt frl:6470180
1000 Zuletzt bearbeitet Fri Dec 01 11:17:45 CET 2023
1000 Objekt bearb. Fri Dec 01 11:17:45 CET 2023
1000 Vgl. frl:6470180
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  1. oai:frl.publisso.de:frl:6470180 |
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