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1000 Titel
  • Radioligand therapy using [177Lu]Lu-PSMA-617 in mCRPC: a pre-VISION single-center analysis
1000 Autor/in
  1. Seifert, Robert |
  2. Kessel, Katharina |
  3. Schlack, Katrin |
  4. Weckesser, Matthias |
  5. Bögemann, Martin |
  6. Rahbar, Kambiz |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-02-16
1000 Erschienen in
1000 Quellenangabe
  • 47(9):2106-2112
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00259-020-04703-3 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338828/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Radioligand therapy with [!##!Methods!#!A total number of 78 consecutive patients with mCRPC and a history of first-line chemotherapy were included in this retrospective analysis. The outcome of patients treated with 6.0 GBq [!##!Results!#!There was no significant difference comparing the rate of > 50% PSA decline or best PSA response between the 6.0 GBq and 7.5 GBq group (35% vs. 54%, p = 0.065; and - 40.2% vs. - 57.8%, p = 0.329). The median estimated survival and PSA-PFS did not significantly differ between the 6.0 GBq and 7.5 GBq groups as well (11.3 vs. 12.7 months, p = 0.384; and 9.5 vs. 12.3 months, p = 0.258). There was no significant difference regarding the change of kidney, liver, and blood cell parameters under therapy between the treatment groups.!##!Conclusion!#!Higher cumulated doses of [
1000 Sacherschließung
lokal Heterocyclic Compounds, 1-Ring/adverse effects [MeSH]
lokal Oncology – Genitourinary
lokal Humans [MeSH]
lokal Prospective Studies [MeSH]
lokal Radioligand therapy
lokal Treatment Outcome [MeSH]
lokal Retrospective Studies [MeSH]
lokal Original Article
lokal VISION Trial
lokal Male [MeSH]
lokal Dipeptides/adverse effects [MeSH]
lokal mCRPC
lokal Prostatic Neoplasms, Castration-Resistant/radiotherapy [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/U2VpZmVydCwgUm9iZXJ0|https://frl.publisso.de/adhoc/uri/S2Vzc2VsLCBLYXRoYXJpbmE=|https://frl.publisso.de/adhoc/uri/U2NobGFjaywgS2F0cmlu|https://frl.publisso.de/adhoc/uri/V2Vja2Vzc2VyLCBNYXR0aGlhcw==|https://frl.publisso.de/adhoc/uri/QsO2Z2VtYW5uLCBNYXJ0aW4=|https://orcid.org/0000-0002-4591-4055
1000 Hinweis
  • DeepGreen-ID: 99ec80a9ac09462cae734e8002a6cb32 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 Erstellt am 2023-11-18T04:48:39.537+0100
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