Microbiota changes associated with ADNP deficiencies: rapid indicators for NAP (CP201) treatment of the ADNP syndrome and beyond

  1. Kapitansky, Oxana
  2. Giladi, Eliezer
  3. Jaljuli, Iman
  4. Bereswill, Stefan
  5. Heimesaat, Markus M.
  6. Gozes, Illana ORCID logo

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WeightNameValue
1000 Titel
  • Microbiota changes associated with ADNP deficiencies: rapid indicators for NAP (CP201) treatment of the ADNP syndrome and beyond
1000 Autor/in
  1. Kapitansky, Oxana |
  2. Giladi, Eliezer |
  3. Jaljuli, Iman |
  4. Bereswill, Stefan |
  5. Heimesaat, Markus M. |
  6. Gozes, Illana |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-02-18
1000 Erschienen in
1000 Quellenangabe
  • 127(2):251-263
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00702-020-02155-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035218/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Activity-dependent neuroprotective protein (ADNP) and its protein snippet NAP (drug candidate CP201) regulate synapse formation and cognitive as well as behavioral functions, in part, through microtubule interaction. Given potential interactions between the microbiome and brain function, we now investigated the potential effects of the ADNP-deficient genotype, mimicking the ADNP syndrome on microbiota composition in the Adnp
1000 Sacherschließung
lokal Autism Spectrum Disorder/physiopathology [MeSH]
lokal Social Cognition [MeSH]
lokal Autism Spectrum Disorder/microbiology [MeSH]
lokal Naphthoquinones/administration
lokal Gastrointestinal Microbiome/drug effects [MeSH]
lokal Mice, Transgenic [MeSH]
lokal Neurology and Preclinical Neurological Studies - Original Article
lokal Male [MeSH]
lokal Naphthoquinones/pharmacokinetics [MeSH]
lokal NAP (CP201)
lokal Disease Models, Animal [MeSH]
lokal Female [MeSH]
lokal Autism
lokal Autism Spectrum Disorder/drug therapy [MeSH]
lokal Naphthoquinones/pharmacology [MeSH]
lokal Activity-dependent neuroprotective protein (ADNP)
lokal Syndrome [MeSH]
lokal Homeodomain Proteins/genetics [MeSH]
lokal Animals [MeSH]
lokal Nerve Tissue Proteins/genetics [MeSH]
lokal Microbiota
lokal Social Behavior [MeSH]
lokal Mice [MeSH]
lokal Behavior
lokal Genotype [MeSH]
lokal Nerve Tissue Proteins/deficiency [MeSH]
lokal Behavior, Animal/drug effects [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/S2FwaXRhbnNreSwgT3hhbmE=|https://frl.publisso.de/adhoc/uri/R2lsYWRpLCBFbGllemVy|https://frl.publisso.de/adhoc/uri/SmFsanVsaSwgSW1hbg==|https://frl.publisso.de/adhoc/uri/QmVyZXN3aWxsLCBTdGVmYW4=|https://frl.publisso.de/adhoc/uri/SGVpbWVzYWF0LCBNYXJrdXMgTS4=|https://orcid.org/0000-0001-9796-2430
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1000 Erstellt am 2023-11-18T05:49:58.632+0100
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