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1000 Titel
  • Access to Meckel’s cave for biopsies of indeterminate lesions: a systematic review
1000 Autor/in
  1. Suero Molina, Eric |
  2. Revuelta Barbero, JM |
  3. Ewelt, C |
  4. Stummer, W |
  5. Carrau, RL |
  6. Prevedello, DM |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-02-10
1000 Erschienen in
1000 Quellenangabe
  • 44(1):249-259
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s10143-020-01247-w |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7850998/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Accessing Meckel's cave (MC) is surgically challenging. Open approaches are complex and often correlated with high morbidity. Endoscopic approaches emerged in the last decade as feasible alternatives to open approaches, especially for sampling indeterminate lesions. This article first analyses available routes to approach Meckel's cave and presents furthermore an illustrative case. We conducted a systematic review and reported according to the guidelines for preferred reporting items for systematic reviews and meta-analyses (PRISMA). Various surgical approaches identified through the search are evaluated and discussed in detail. Additionally, we report on a case of woman with a lesion in MC, which was accessed through an endoscopic transpterygoid approach subsequently diagnosed as a diffuse large B cell lymphoma. Our search delivered 75 articles that included case reports (n = 21), cadaveric studies (n = 32), clinical articles (n = 16), review of the literatures (n = 3), as well as technical notes (n = 2) and a radiological manuscript (n = 1). Open routes included lateral approaches with many variations, mainly intra- and extradural pterional approaches and anterior petrosal, as well as a retrosigmoid intradural suprameatal and a lateral transorbital approach. Endoscopically, MC was reached via approaches that included transpterygoid, transorbital or infraorbital fissure routes. Percutaneous approaches, e.g. through the foramen ovale, were also described. Multiple surgical approaches to MC are currently available. Their different characteristics as well as individual patient factors, such as clinical history and the localization of the disease, have to be considered when choosing a surgical corridor. Studies included in this review highlight the endonasal endoscopic transpterygoidal technique as an excellent corridor for biopsies in the ventral MC.
1000 Sacherschließung
lokal Skull Base/pathology [MeSH]
lokal Meckel’s cave
lokal Humans [MeSH]
lokal Neuroendoscopy/methods [MeSH]
lokal Endoscopic endonasal approach
lokal Cranial Fossa, Middle/surgery [MeSH]
lokal Approaches
lokal Biopsy/methods [MeSH]
lokal Skull Base/surgery [MeSH]
lokal Indeterminate lesions
lokal Guidelines as Topic [MeSH]
lokal Skull base surgery
lokal Review
lokal Cranial Fossa, Middle/pathology [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-5652-2105|https://frl.publisso.de/adhoc/uri/UmV2dWVsdGEgQmFyYmVybywgSk0=|https://frl.publisso.de/adhoc/uri/RXdlbHQsIEM=|https://frl.publisso.de/adhoc/uri/U3R1bW1lciwgVw==|https://frl.publisso.de/adhoc/uri/Q2FycmF1LCBSTA==|https://frl.publisso.de/adhoc/uri/UHJldmVkZWxsbywgRE0=
1000 Hinweis
  • DeepGreen-ID: 030562a817c24a76b1f1c19831625c5c ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 @id frl:6470538.rdf
1000 Erstellt am 2023-11-18T07:05:00.763+0100
1000 Erstellt von 322
1000 beschreibt frl:6470538
1000 Zuletzt bearbeitet 2023-12-01T12:13:41.786+0100
1000 Objekt bearb. Fri Dec 01 12:13:41 CET 2023
1000 Vgl. frl:6470538
1000 Oai Id
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