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1000 Titel
  • Safety metric profiling in surgery for temporal glioblastoma: lobectomy as a supra-total resection regime preserves perioperative standard quality rates
1000 Autor/in
  1. Schneider, Matthias |
  2. Ilic, Inja |
  3. Potthoff, Anna-Laura |
  4. Hamed, Motaz |
  5. Schäfer, Niklas |
  6. Velten, Markus |
  7. Güresir, Erdem |
  8. Herrlinger, Ulrich |
  9. Borger, Valeri |
  10. Vatter, Hartmut |
  11. Schuss, Patrick |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-09-29
1000 Erschienen in
1000 Quellenangabe
  • 149(3):455-461
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s11060-020-03629-y |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7609430/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Introduction!#!Supra-total resection in terms of anterior temporal lobectomy (ATL) has gained growing attention with regard to superior long-term disease control for temporal-located glioblastoma. However, aggressive onco-surgical approaches-geared beyond conventional gross total resections (GTR)-may be associated with peri- and postoperative unfavorable events which significantly worsen initial favorable postoperative outcome. In the current study we analyzed our institutional database with regard to patient safety indicators (PSIs), hospital-acquired conditions (HACs) and specific cranial surgery-related complications (CSC) as high standard quality metric profiles in patients that had undergone surgery for temporal glioblastoma.!##!Methods!#!Between 2012 and 2018, 61 patients with temporal glioblastoma underwent GTR or temporal lobectomy at the authors' institution. Both groups of differing resection modalities were analyzed with regard to the incidence of PSIs, HACs and CSCs.!##!Results!#!Overall, we found 6 PSI and 2 HAC events. Postoperative hemorrhage (3 out of 61 patients; 5%) and catheter-associated urinary tract infection (2 out 61 patients; 3%) were identified as the most frequent PSIs and HACs. PSIs were present in 1 out of 41 patients (5%) for the temporal GTR and 2 out of 20 patients for the lobectomy group (p = 1.0). Respective rates for PSIs were 5 of 41 (12%) and 1 of 20 (5%) (p = 0.7). Further, CSCs did not yield significant differences between these two resection modalities (p = 1.0).!##!Conclusion!#!With regard to ATL and GTR as differing onco-surgical approaches these data suggest ATL in terms of an aggressive supra-total resection strategy to preserve perioperative standard safety metric profiles.
1000 Sacherschließung
lokal Female [MeSH]
lokal Follow-Up Studies [MeSH]
lokal Glioblastoma/surgery [MeSH]
lokal Humans [MeSH]
lokal Brain Neoplasms/surgery [MeSH]
lokal Retrospective Studies [MeSH]
lokal Middle Aged [MeSH]
lokal Gross total resection
lokal Hospitalization/statistics
lokal Glioblastoma/pathology [MeSH]
lokal Postoperative complication profiling
lokal Patient Safety/standards [MeSH]
lokal Temporal glioblastoma surgery
lokal Male [MeSH]
lokal Prognosis [MeSH]
lokal Clinical Study
lokal Quality of Health Care/standards [MeSH]
lokal Anterior temporal lobectomy
lokal Neurosurgical Procedures/standards [MeSH]
lokal Brain Neoplasms/pathology [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-6025-7479|https://frl.publisso.de/adhoc/uri/SWxpYywgSW5qYQ==|https://frl.publisso.de/adhoc/uri/UG90dGhvZmYsIEFubmEtTGF1cmE=|https://frl.publisso.de/adhoc/uri/SGFtZWQsIE1vdGF6|https://frl.publisso.de/adhoc/uri/U2Now6RmZXIsIE5pa2xhcw==|https://frl.publisso.de/adhoc/uri/VmVsdGVuLCBNYXJrdXM=|https://frl.publisso.de/adhoc/uri/R8O8cmVzaXIsIEVyZGVt|https://frl.publisso.de/adhoc/uri/SGVycmxpbmdlciwgVWxyaWNo|https://frl.publisso.de/adhoc/uri/Qm9yZ2VyLCBWYWxlcmk=|https://frl.publisso.de/adhoc/uri/VmF0dGVyLCBIYXJ0bXV0|https://frl.publisso.de/adhoc/uri/U2NodXNzLCBQYXRyaWNr
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1000 Erstellt am 2023-11-18T09:06:02.559+0100
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