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1000 Titel
  • Glial Factors Regulating White Matter Development and Pathologies of the Cerebellum
1000 Autor/in
  1. Revuelta, Miren |
  2. Scheuer, Till |
  3. Chew, Li-Jin |
  4. Schmitz, Thomas |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-01-23
1000 Erschienen in
1000 Quellenangabe
  • 45(3):643-655
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s11064-020-02961-z |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058568/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • The cerebellum is a brain region that undergoes extremely dynamic growth during perinatal and postnatal development which is regulated by the proper interaction between glial cells and neurons with a complex concert of growth factors, chemokines, cytokines, neurotransmitters and transcriptions factors. The relevance of cerebellar functions for not only motor performance but also for cognition, emotion, memory and attention is increasingly being recognized and acknowledged. Since perturbed circuitry of cerebro-cerebellar trajectories can play a role in many central nervous system pathologies and thereby contribute to neurological symptoms in distinct neurodevelopmental and neurodegenerative diseases, is it the aim with this mini-review to highlight the pathways of glia-glia interplay being involved. The designs of future treatment strategies may hence be targeted to molecular pathways also playing a role in development and disease of the cerebellum.
1000 Sacherschließung
lokal Cerebellum/pathology [MeSH]
lokal Pathologies
lokal Development
lokal Humans [MeSH]
lokal Original Paper
lokal Therapy
lokal Signal Transduction [MeSH]
lokal Cerebellum
lokal Animals [MeSH]
lokal Neuroglia/pathology [MeSH]
lokal White Matter/pathology [MeSH]
lokal Glia
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/UmV2dWVsdGEsIE1pcmVu|https://frl.publisso.de/adhoc/uri/U2NoZXVlciwgVGlsbA==|https://frl.publisso.de/adhoc/uri/Q2hldywgTGktSmlu|https://orcid.org/0000-0001-8193-8970
1000 Hinweis
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1000 Erstellt am 2023-11-18T09:06:51.908+0100
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