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1000 Titel
  • Management of children with fever and neutropenia: results of a survey in 51 pediatric cancer centers in Germany, Austria, and Switzerland
1000 Autor/in
  1. Scheler, Max |
  2. Lehrnbecher, Thomas |
  3. Groll, Andreas H. |
  4. Volland, Ruth |
  5. Laws, Hans-Jürgen |
  6. Ammann, Roland A. |
  7. Agyeman, Philipp |
  8. Attarbaschi, Andishe |
  9. Lux, Margaux |
  10. Simon, Arne |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-06-10
1000 Erschienen in
1000 Quellenangabe
  • 48(4):607-618
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s15010-020-01462-z |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7395019/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Purpose!#!Investigation of the current practice of diagnostics and treatment in pediatric cancer patients with febrile neutropenia.!##!Methods!#!On behalf of the German Society for Pediatric Oncology and Hematology and the German Society for Pediatric Infectious Diseases, an Internet-based survey was conducted in 2016 concerning the management of febrile neutropenia in pediatric oncology centers (POC). This survey accompanied the release of the corresponding German guideline to document current practice before its implementation in clinical practice.!##!Results!#!In total, 51 POCs participated (response rate 73%; 43 from Germany, and 4 each from Austria and Switzerland). Identified targets for antimicrobial stewardship concerned blood culture diagnostics, documentation of the time to antibiotics, the use of empirical combination therapy, drug monitoring of aminoglycosides, the time to escalation in patients with persisting fever, minimal duration of IV treatment, sequential oral treatment in patients with persisting neutropenia, indication for and choice of empirical antifungal treatment, and the local availability of a pediatric infectious diseases consultation service.!##!Conclusion!#!This survey provides useful information for local antibiotic stewardship teams to improve the current practice referring to the corresponding national and international guidelines.
1000 Sacherschließung
lokal Infant, Newborn [MeSH]
lokal Adolescent [MeSH]
lokal Febrile neutropenia
lokal Humans [MeSH]
lokal Cancer Care Facilities/statistics
lokal Antimicrobial Stewardship [MeSH]
lokal Neutropenia/complications [MeSH]
lokal Fever/therapy [MeSH]
lokal Antimicrobial treatment
lokal Neutropenia/therapy [MeSH]
lokal Infant [MeSH]
lokal Switzerland [MeSH]
lokal Neoplasms/complications [MeSH]
lokal Germany [MeSH]
lokal Original Paper
lokal Pediatric cancer patients
lokal Fever/complications [MeSH]
lokal Austria [MeSH]
lokal Child [MeSH]
lokal Child, Preschool [MeSH]
lokal Survey
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/U2NoZWxlciwgTWF4|https://frl.publisso.de/adhoc/uri/TGVocm5iZWNoZXIsIFRob21hcw==|https://frl.publisso.de/adhoc/uri/R3JvbGwsIEFuZHJlYXMgSC4=|https://frl.publisso.de/adhoc/uri/Vm9sbGFuZCwgUnV0aA==|https://frl.publisso.de/adhoc/uri/TGF3cywgSGFucy1Kw7xyZ2Vu|https://frl.publisso.de/adhoc/uri/QW1tYW5uLCBSb2xhbmQgQS4=|https://frl.publisso.de/adhoc/uri/QWd5ZW1hbiwgUGhpbGlwcA==|https://frl.publisso.de/adhoc/uri/QXR0YXJiYXNjaGksIEFuZGlzaGU=|https://frl.publisso.de/adhoc/uri/THV4LCBNYXJnYXV4|https://orcid.org/0000-0001-9558-3330
1000 Hinweis
  • DeepGreen-ID: 9514761f6e63499dbe0cf6e746b2507a ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 Erstellt am 2023-11-18T12:19:06.021+0100
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1000 Zuletzt bearbeitet Fri Dec 01 14:04:53 CET 2023
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