Allogeneic hematopoietic cell transplantation for patients with TP53 mutant or deleted chronic lymphocytic leukemia: Results of a prospective observational study

  1. Schetelig, Johannes ORCID logo
  2. Hoek, Jennifer
  3. Stilgenbauer, Stephan
  4. Middeke, Jan Moritz ORCID logo
  5. Andersen, Niels Smedegaard
  6. Fox, Christopher Paul ORCID logo
  7. Lenhoff, Stig
  8. Volin, Liisa
  9. Shimoni, Avichai
  10. Schroyens, Wilfried
  11. van Gelder, Michel
  12. Bunjes, Donald
  13. van Biezen, Anja
  14. Baldauf, Henning
  15. de Wreede, Liesbeth C.
  16. Tournilhac, Olivier
  17. Kröger, Nicolaus ORCID logo
  18. Yakoub-Agha, Ibrahim
  19. Dreger, Peter ORCID logo

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WeightNameValue
1000 Titel
  • Allogeneic hematopoietic cell transplantation for patients with TP53 mutant or deleted chronic lymphocytic leukemia: Results of a prospective observational study
1000 Autor/in
  1. Schetelig, Johannes |
  2. Hoek, Jennifer |
  3. Stilgenbauer, Stephan |
  4. Middeke, Jan Moritz |
  5. Andersen, Niels Smedegaard |
  6. Fox, Christopher Paul |
  7. Lenhoff, Stig |
  8. Volin, Liisa |
  9. Shimoni, Avichai |
  10. Schroyens, Wilfried |
  11. van Gelder, Michel |
  12. Bunjes, Donald |
  13. van Biezen, Anja |
  14. Baldauf, Henning |
  15. de Wreede, Liesbeth C. |
  16. Tournilhac, Olivier |
  17. Kröger, Nicolaus |
  18. Yakoub-Agha, Ibrahim |
  19. Dreger, Peter |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-08-16
1000 Erschienen in
1000 Quellenangabe
  • 56(3):692-695
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1038/s41409-020-01013-y |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8589674/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Schwannomas are tumors of the peripheral nervous system, consisting of different cell types. These include tumorigenic Schwann cells, axons, macrophages, T cells, fibroblasts, blood vessels, and an extracellular matrix. All cell types involved constitute an intricate 'tumor microenvironment' and play relevant roles in the development and progression of schwannomas. Although Nf2 tumor suppressor gene-deficient Schwann cells are the primary tumorigenic element and principle focus of current research efforts, evidence is accumulating regarding the contributory roles of other cell types in schwannoma pathology. In this review, we aim to provide an overview of intra- and intercellular mechanisms contributing to schwannoma formation. 'Genes load the gun, environment pulls the trigger.' -George A. Bray.
1000 Sacherschließung
lokal Leukemia, Lymphocytic, Chronic, B-Cell/genetics [MeSH]
lokal Chronic lymphocytic leukaemia
lokal Humans [MeSH]
lokal Prospective Studies [MeSH]
lokal Leukemia, Lymphocytic, Chronic, B-Cell/therapy [MeSH]
lokal Hematopoietic Stem Cell Transplantation [MeSH]
lokal Stem-cell therapies
lokal Tumor Suppressor Protein p53/genetics [MeSH]
lokal Correspondence
lokal Transplantation, Homologous [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-2780-2981|https://frl.publisso.de/adhoc/uri/SG9laywgSmVubmlmZXI=|https://frl.publisso.de/adhoc/uri/U3RpbGdlbmJhdWVyLCBTdGVwaGFu|https://orcid.org/0000-0003-3250-293X|https://frl.publisso.de/adhoc/uri/QW5kZXJzZW4sIE5pZWxzIFNtZWRlZ2FhcmQ=|https://orcid.org/0000-0002-6322-9254|https://frl.publisso.de/adhoc/uri/TGVuaG9mZiwgU3RpZw==|https://frl.publisso.de/adhoc/uri/Vm9saW4sIExpaXNh|https://frl.publisso.de/adhoc/uri/U2hpbW9uaSwgQXZpY2hhaQ==|https://frl.publisso.de/adhoc/uri/U2Nocm95ZW5zLCBXaWxmcmllZA==|https://frl.publisso.de/adhoc/uri/dmFuIEdlbGRlciwgTWljaGVs|https://frl.publisso.de/adhoc/uri/QnVuamVzLCBEb25hbGQ=|https://frl.publisso.de/adhoc/uri/dmFuIEJpZXplbiwgQW5qYQ==|https://frl.publisso.de/adhoc/uri/QmFsZGF1ZiwgSGVubmluZw==|https://frl.publisso.de/adhoc/uri/ZGUgV3JlZWRlLCBMaWVzYmV0aCBDLg==|https://frl.publisso.de/adhoc/uri/VG91cm5pbGhhYywgT2xpdmllcg==|https://orcid.org/0000-0002-2961-4183|https://frl.publisso.de/adhoc/uri/WWFrb3ViLUFnaGEsIElicmFoaW0=|https://orcid.org/0000-0002-7429-8570
1000 Hinweis
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1000 Erstellt am 2023-11-18T12:53:00.727+0100
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