Metabolic and amyloid PET network reorganization in Alzheimer’s disease: differential patterns and partial volume effects

  1. Gonzalez Escamilla, Gabriel ORCID logo
  2. Miederer, Isabelle
  3. Grothe, Michel J.
  4. Schreckenberger, Mathias
  5. Muthuraman, Muthuraman
  6. Groppa, Sergiu

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1000 Titel
  • Metabolic and amyloid PET network reorganization in Alzheimer’s disease: differential patterns and partial volume effects
1000 Autor/in
  1. Gonzalez Escamilla, Gabriel |
  2. Miederer, Isabelle |
  3. Grothe, Michel J. |
  4. Schreckenberger, Mathias |
  5. Muthuraman, Muthuraman |
  6. Groppa, Sergiu |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-03-03
1000 Erschienen in
1000 Quellenangabe
  • 15(1):190-204
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s11682-019-00247-9 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7835313/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Alzheimer's disease (AD) is a neurodegenerative disorder, considered a disconnection syndrome with regional molecular pattern abnormalities quantifiable by the aid of PET imaging. Solutions for accurate quantification of network dysfunction are scarce. We evaluate the extent to which PET molecular markers reflect quantifiable network metrics derived through the graph theory framework and how partial volume effects (PVE)-correction (PVEc) affects these PET-derived metrics 75 AD patients and 126 cognitively normal older subjects (CN). Therefore our goal is twofold: 1) to evaluate the differential patterns of [
1000 Sacherschließung
lokal Amyloid/metabolism [MeSH]
lokal Brain/diagnostic imaging [MeSH]
lokal Brain molecular networks
lokal Humans [MeSH]
lokal Aniline Compounds [MeSH]
lokal Alzheimer Disease/diagnostic imaging [MeSH]
lokal MRI
lokal Fluorodeoxyglucose F18 [MeSH]
lokal PET
lokal Alzheimer’s disease
lokal Magnetic Resonance Imaging [MeSH]
lokal Brain/metabolism [MeSH]
lokal Positron-Emission Tomography [MeSH]
lokal Original Research
lokal Partial volume effects correction
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-7209-1736|https://frl.publisso.de/adhoc/uri/TWllZGVyZXIsIElzYWJlbGxl|https://frl.publisso.de/adhoc/uri/R3JvdGhlLCBNaWNoZWwgSi4=|https://frl.publisso.de/adhoc/uri/U2NocmVja2VuYmVyZ2VyLCBNYXRoaWFz|https://frl.publisso.de/adhoc/uri/TXV0aHVyYW1hbiwgTXV0aHVyYW1hbg==|https://frl.publisso.de/adhoc/uri/R3JvcHBhLCBTZXJnaXU=
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1000 Erstellt am 2023-11-18T14:03:13.609+0100
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1000 Zuletzt bearbeitet 2024-04-03T14:24:21.449+0200
1000 Objekt bearb. Wed Apr 03 14:24:21 CEST 2024
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