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1000 Titel
  • The Gut Ecosystem: A Critical Player in Stroke
1000 Autor/in
  1. Delgado Jiménez, Rosa |
  2. Benakis, Corinne |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-11-18
1000 Erschienen in
1000 Quellenangabe
  • 23(2):236-241
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s12017-020-08633-z |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8128731/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • The intestinal microbiome is emerging as a critical factor in health and disease. The microbes, although spatially restricted to the gut, are communicating and modulating the function of distant organs such as the brain. Stroke and other neurological disorders are associated with a disrupted microbiota. In turn, stroke-induced dysbiosis has a major impact on the disease outcome by modulating the immune response. In this review, we present current knowledge on the role of the gut microbiome in stroke, one of the most devastating brain disorders worldwide with very limited therapeutic options, and we discuss novel insights into the gut-immune-brain axis after an ischemic insult. Understanding the nature of the gut bacteria-brain crosstalk may lead to microbiome-based therapeutic approaches that can improve patient recovery.
1000 Sacherschließung
lokal Dendritic Cells/immunology [MeSH]
lokal Dysbiosis/complications [MeSH]
lokal Dysbiosis/physiopathology [MeSH]
lokal Brain Ischemia/etiology [MeSH]
lokal Inflammation [MeSH]
lokal Bacterial Translocation [MeSH]
lokal Gastrointestinal Microbiome/drug effects [MeSH]
lokal Metabolites
lokal Stroke
lokal Brain Damage, Chronic/prevention
lokal Immune system
lokal Gastrointestinal Motility [MeSH]
lokal Dysbiosis/immunology [MeSH]
lokal Intestines/blood supply [MeSH]
lokal Norepinephrine/metabolism [MeSH]
lokal Microbiome
lokal Brain Ischemia/therapy [MeSH]
lokal Disease Models, Animal [MeSH]
lokal Mini-Reviews
lokal Fermentation [MeSH]
lokal Stroke/therapy [MeSH]
lokal Anti-Bacterial Agents/therapeutic use [MeSH]
lokal Fatty Acids, Volatile/metabolism [MeSH]
lokal Humans [MeSH]
lokal Infarction/pathology [MeSH]
lokal T-Lymphocytes, Regulatory/immunology [MeSH]
lokal Aging [MeSH]
lokal Animals [MeSH]
lokal Mice [MeSH]
lokal Gut-brain axis
lokal Brain Damage, Chronic/etiology [MeSH]
lokal Brain-Gut Axis/drug effects [MeSH]
lokal Stroke/microbiology [MeSH]
lokal Brain Ischemia/microbiology [MeSH]
lokal Stroke/etiology [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/RGVsZ2FkbyBKaW3DqW5leiwgUm9zYQ==|https://orcid.org/0000-0001-6463-7949
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1000 Dateien
  1. The Gut Ecosystem: A Critical Player in Stroke
1000 Objektart article
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1000 Erstellt am 2023-11-18T14:46:07.291+0100
1000 Erstellt von 322
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1000 Zuletzt bearbeitet 2024-04-04T10:46:27.267+0200
1000 Objekt bearb. Thu Apr 04 10:46:27 CEST 2024
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