Constitutive TSH receptor activation as a hallmark of thyroid autonomy

  1. Führer, Dagmar

Download
s12020-020-02270-z.pdf 605,48KB
WeightNameValue
1000 Titel
  • Constitutive TSH receptor activation as a hallmark of thyroid autonomy
1000 Autor/in
  1. Führer, Dagmar |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-04-17
1000 Erschienen in
1000 Quellenangabe
  • 68(2):274-278
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s12020-020-02270-z |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266789/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Since its cloning more than 30 years ago, the thyrotropin receptor (TSHR) has emerged as a pivotal player in thyroid physiology and pathophysiology. In particular, hyperthyroidism due to autoimmune disease or thyroid autonomy is linked with TSHR activation via autoantibodies or mutations respectively. This review summarises clinical aspects of constitutive TSH receptor activation by naturally occurring somatic or germline TSHR mutations resulting in TSH-independent thyroid function and cell proliferation.
1000 Sacherschließung
lokal Mutation [MeSH]
lokal Inverse agonist and antagonists
lokal Humans [MeSH]
lokal Toxic adenoma
lokal Toxic multinodular goitre
lokal Somatic and germline mutation
lokal Thyrotropin [MeSH]
lokal Mini Review
lokal TSH receptor
lokal Hereditary non-autoimmune hyperthyroidism
lokal Receptors, Thyrotropin/genetics [MeSH]
lokal Hyperthyroidism [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/RsO8aHJlciwgRGFnbWFy
1000 Hinweis
  • DeepGreen-ID: 2e3499609a324000a00d27fb98b97814 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
1000 Label
1000 Dateien
  1. Constitutive TSH receptor activation as a hallmark of thyroid autonomy
    Constitutive TSH receptor activation as a hallmark of thyroid autonomy
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6471674.rdf
1000 Erstellt am 2023-11-18T14:56:05.678+0100
1000 Erstellt von 322
1000 beschreibt frl:6471674
1000 Zuletzt bearbeitet Fri Apr 05 12:34:51 CEST 2024
1000 Objekt bearb. Fri Apr 05 12:34:51 CEST 2024
1000 Vgl. frl:6471674
1000 Oai Id
  1. oai:frl.publisso.de:frl:6471674 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

View source