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1000 Titel
  • Molecular imaging in nuclear cardiology: Pathways to individual precision medicine
1000 Autor/in
  1. Glasenapp, A. |
  2. Hess, A. |
  3. Thackeray, J. T. |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-09-06
1000 Erschienen in
1000 Quellenangabe
  • 27(6):2195-2201
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s12350-020-02319-6 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749093/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Growth of molecular imaging bears potential to transform nuclear cardiology from a primarily diagnostic method to a precision medicine tool. Molecular targets amenable for imaging and therapeutic intervention are particularly promising to facilitate risk stratification, patient selection and exquisite guidance of novel therapies, and interrogation of systems-based interorgan communication. Non-invasive visualization of pathobiology provides valuable insights into the progression of disease and response to treatment. Specifically, inflammation, fibrosis, and neurohormonal signaling, central to the progression of cardiovascular disease and emerging therapeutic strategies, have been investigated by molecular imaging. As the number of radioligands grows, careful investigation of the binding properties and added-value of imaging should be prioritized to identify high-potential probes and facilitate translation to clinical applications. In this review, we discuss the current state of molecular imaging in cardiovascular medicine, and the challenges and opportunities ahead for cardiovascular molecular imaging to navigate the path from diagnosis to prognosis to personalized medicine.
1000 Sacherschließung
lokal Positron emission tomography
lokal Cardiology/methods [MeSH]
lokal Molecular Imaging/methods [MeSH]
lokal Fibrosis [MeSH]
lokal Hormones/metabolism [MeSH]
lokal Sympathetic nervous system
lokal Cardiovascular disease
lokal Humans [MeSH]
lokal Inflammation
lokal Neurons/metabolism [MeSH]
lokal Inflammation [MeSH]
lokal Treatment Outcome [MeSH]
lokal Precision Medicine/methods [MeSH]
lokal Cytokines/metabolism [MeSH]
lokal Animals [MeSH]
lokal Fibrosis
lokal Risk [MeSH]
lokal Cardiovascular System [MeSH]
lokal Mice [MeSH]
lokal Cardiovascular Diseases/diagnostic imaging [MeSH]
lokal Positron-Emission Tomography [MeSH]
lokal Molecular Imaging Corner
lokal Cardiovascular Diseases/therapy [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/R2xhc2VuYXBwLCBBLg==|https://frl.publisso.de/adhoc/uri/SGVzcywgQS4=|https://frl.publisso.de/adhoc/uri/VGhhY2tlcmF5LCBKLiBULg==
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1000 Erstellt am 2023-11-18T16:50:00.598+0100
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1000 Zuletzt bearbeitet 2024-04-04T11:01:43.610+0200
1000 Objekt bearb. Thu Apr 04 11:01:43 CEST 2024
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