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1000 Titel
  • Performance evaluation of fifth-generation ultra-high-resolution SPECT system with two stationary detectors and multi-pinhole imaging
1000 Autor/in
  1. Hoffmann, Jan V. |
  2. Janssen, Jan P. |
  3. Kanno, Takayuki |
  4. Shibutani, Takayuki |
  5. Onoguchi, Masahisa |
  6. Lapa, Constantin |
  7. Grunz, Jan-Peter |
  8. Buck, Andreas K. |
  9. Higuchi, Takahiro |
1000 Erscheinungsjahr 2020
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2020-11-02
1000 Erschienen in
1000 Quellenangabe
  • 7(1):64
1000 Copyrightjahr
  • 2020
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s40658-020-00335-6 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7606439/ |
1000 Publikationsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Small-animal single-photon emission computed tomography (SPECT) systems with multi-pinhole collimation and large stationary detectors have advantages compared to systems with moving small detectors. These systems benefit from less labour-intensive maintenance and quality control as fewer prone parts are moving, higher accuracy for focused scans and maintaining high resolution with increased sensitivity due to focused pinholes on the field of view. This study aims to investigate the performance of a novel ultra-high-resolution scanner with two-detector configuration (U-SPECT5-E) and to compare its image quality to a conventional micro-SPECT system with three stationary detectors (U-SPECT!##!Methods!#!The new U-SPECT5-E with two stationary detectors was used for acquiring data with !##!Results!#!Peak sensitivity was 237 cps/MBq (XUHR-M), 847 cps/MBq (GP-M), 2054 cps/MBq (UHS-M) for U-SPECT5-E and 1710 cps/MBq (GP-M) for U-SPECT!##!Conclusions!#!While uniformity and sensitivity are negatively affected by the absence of a third detector, the investigated U-SPECT5-E system with two stationary detectors delivers excellent spatial resolution and CNR comparable to the performance of an established three-detector-setup.
1000 Sacherschließung
lokal Small-animal imaging, SPECT
lokal Original Research
lokal Post-reconstruction filtering
lokal Collimator
lokal Mouse
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/SG9mZm1hbm4sIEphbiBWLg==|https://frl.publisso.de/adhoc/uri/SmFuc3NlbiwgSmFuIFAu|https://frl.publisso.de/adhoc/uri/S2Fubm8sIFRha2F5dWtp|https://frl.publisso.de/adhoc/uri/U2hpYnV0YW5pLCBUYWtheXVraQ==|https://frl.publisso.de/adhoc/uri/T25vZ3VjaGksIE1hc2FoaXNh|https://frl.publisso.de/adhoc/uri/TGFwYSwgQ29uc3RhbnRpbg==|https://frl.publisso.de/adhoc/uri/R3J1bnosIEphbi1QZXRlcg==|https://frl.publisso.de/adhoc/uri/QnVjaywgQW5kcmVhcyBLLg==|https://orcid.org/0000-0001-9711-7835
1000 Hinweis
  • DeepGreen-ID: 198a7ef22ef943d1847c27f12b01b5a6 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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1000 Erstellt am 2023-11-18T19:44:12.058+0100
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1000 Zuletzt bearbeitet 2024-04-05T12:44:00.036+0200
1000 Objekt bearb. Fri Apr 05 12:44:00 CEST 2024
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  1. oai:frl.publisso.de:frl:6472338 |
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