Polyfunctional KLRG-1+CD57+ Senescent CD4+ T Cells Infiltrate Tumors and Are Expanded in Peripheral Blood From Breast Cancer Patients

  1. Ramello, Maria C.
  2. Núñez, Nicolás G.
  3. Tosello Boari, Jimena
  4. Bossio, Sabrina N.
  5. Canale, Fernando P.
  6. Abrate, Carolina
  7. Ponce, Nicolas
  8. Del Castillo, Andrés
  9. Ledesma, Marta
  10. Viel, Sophie
  11. Richer, Wilfrid
  12. Sedlik, Christine
  13. Tiraboschi, Carolina
  14. Muñoz, Marcos
  15. Compagno, Daniel
  16. Gruppi, Adriana
  17. Acosta Rodríguez, Eva V.
  18. Piaggio, Eliane
  19. Montes, Carolina L.

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WeightNameValue
1000 Titel
  • Polyfunctional KLRG-1+CD57+ Senescent CD4+ T Cells Infiltrate Tumors and Are Expanded in Peripheral Blood From Breast Cancer Patients
1000 Autor/in
  1. Ramello, Maria C. |
  2. Núñez, Nicolás G. |
  3. Tosello Boari, Jimena |
  4. Bossio, Sabrina N. |
  5. Canale, Fernando P. |
  6. Abrate, Carolina |
  7. Ponce, Nicolas |
  8. Del Castillo, Andrés |
  9. Ledesma, Marta |
  10. Viel, Sophie |
  11. Richer, Wilfrid |
  12. Sedlik, Christine |
  13. Tiraboschi, Carolina |
  14. Muñoz, Marcos |
  15. Compagno, Daniel |
  16. Gruppi, Adriana |
  17. Acosta Rodríguez, Eva V. |
  18. Piaggio, Eliane |
  19. Montes, Carolina L. |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-07-27
1000 Erschienen in
1000 Quellenangabe
  • 12
1000 Copyrightjahr
  • 2021
1000 Embargo
  • 2022-01-29
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.3389/fimmu.2021.713132 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353459/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Abstract/Summary
  • Senescent T cells have been described during aging, chronic infections, and cancer; however, a comprehensive study of the phenotype, function, and transcriptional program of this T cell population in breast cancer (BC) patients is missing. Compared to healthy donors (HDs), BC patients exhibit an accumulation of KLRG-1
1000 Sacherschließung
lokal breast cancer
lokal T-Lymphocyte Subsets/immunology [MeSH]
lokal Cytotoxicity, Immunologic [MeSH]
lokal CD57 Antigens/metabolism [MeSH]
lokal polyfunctional T cells
lokal Cellular Senescence/immunology [MeSH]
lokal T-Lymphocyte Subsets/metabolism [MeSH]
lokal Immunophenotyping [MeSH]
lokal Lymphocytes, Tumor-Infiltrating/pathology [MeSH]
lokal Case-Control Studies [MeSH]
lokal T-Lymphocyte Subsets/pathology [MeSH]
lokal Cellular Senescence/genetics [MeSH]
lokal CD4-Positive T-Lymphocytes/metabolism [MeSH]
lokal Receptors, Immunologic/metabolism [MeSH]
lokal Breast Neoplasms/pathology [MeSH]
lokal Breast Neoplasms/etiology [MeSH]
lokal Female [MeSH]
lokal Immunology
lokal Lymphocyte Count [MeSH]
lokal cytotoxic CD4 T cells
lokal Humans [MeSH]
lokal KLRG-1
lokal Breast Neoplasms/metabolism [MeSH]
lokal Lymphocytes, Tumor-Infiltrating/metabolism [MeSH]
lokal Lymphocytes, Tumor-Infiltrating/immunology [MeSH]
lokal senescent T cells
lokal CD4-Positive T-Lymphocytes/immunology [MeSH]
lokal CD57
lokal Lectins, C-Type/metabolism [MeSH]
lokal Gene Expression Profiling [MeSH]
1000 Liste der Beteiligten
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1000 Erstellt am 2024-04-11T11:19:12.873+0200
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