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1000 Titel
  • A U-Shaped Relationship Between Selenium Concentrations and All-Cause or Cardiovascular Mortality in Patients With Hypertension
1000 Autor/in
  1. Tan, Qiu-hong |
  2. Huang, Yu-qing |
  3. Liu, Xiao-cong |
  4. Liu, Lin |
  5. Lo, Kenneth |
  6. Chen, Ji-yan |
  7. Feng, Ying-qing |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-07-30
1000 Erschienen in
1000 Quellenangabe
  • 8
1000 Copyrightjahr
  • 2021
1000 Embargo
  • 2022-02-01
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.3389/fcvm.2021.671618 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8360873/ |
1000 Publikationsstatus
1000 Abstract/Summary
  • Serious iatrogenic bowel injuries during screening colonoscopy are rare events. If a perforation is detected during colonoscopy, endoscopic therapy can be attempted depending on the size and type as well as local endoscopic experience. We report the case of a 54-year-old female patient who was treated by endoscopic vacuum therapy (EVT) for a rectal perforation she had suffered during an outpatient screening colonoscopy. Two hours after the complication, an emergency endoscopy was performed. A perforation of the lower third of the rectum with a longitudinal diameter of 4 cm and a depth of 2.5 cm was detected. Due to the deep defect and the suspected increased risk of abscess formation after mechanical perforation closure with endoclips, we decided to perform EVT. The therapy was performed over a total period of 7 days. The patient was symptom free at all times. On the 2nd and 5th day, the endoscopic findings were re-evaluated and the inserted endosponges were changed. The sponge was adjusted to the wound conditions at each check and its length was gradually shortened. The endoscopic findings improved steadily. The EVT was completed after 7 days with the result of complete wound closure. The inflammatory parameters dropped continuously from day 1. On day 8, the patient could be discharged from inpatient treatment. No complications occurred in the post-inpatient course. This case is an example of successful EVT after iatrogenic rectal perforation. EVT should be considered for iatrogenic rectal perforation when signs of systemic inflammation are present and primary mechanical wound closure appears critical due to the depth of the defect and the presumed risk of abscess formation.
1000 Sacherschließung
lokal all-cause mortality
lokal cardiovascular mortality
lokal Cardiovascular Medicine
lokal hypertension
lokal selenium
lokal risk factors
1000 Liste der Beteiligten
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