Download
s41598-024-57025-x.pdf 1,24MB
WeightNameValue
1000 Titel
  • Association among childhood adversity and susceptibility to interference during varying salience: two studies in healthy males
1000 Autor/in
  1. Amedick, Greta |
  2. Krylova, Marina |
  3. Mayer, Kathrin |
  4. Izyurov, Igor |
  5. Herrmann, Luisa |
  6. Martens, Louise |
  7. Kasties, Vanessa |
  8. Heller, Johanna |
  9. Li, Meng |
  10. van der Meer, Johan |
  11. Croy, Ilona |
  12. Engert, Veronika |
  13. Walter, Martin |
  14. Colic, Lejla |
1000 Erscheinungsjahr 2024
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-03-25
1000 Erschienen in
1000 Quellenangabe
  • 14(1):7050
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1038/s41598-024-57025-x |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10963761/ |
1000 Ergänzendes Material
  • https://www.nature.com/articles/s41598-024-57025-x#Sec19 |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Childhood adversity, a prevalent experience, is related to a higher risk for externalizing and internalizing psychopathology. Alterations in the development of cognitive processes, for example in the attention-interference domain may link childhood adversity and psychopathology. Interfering stimuli can vary in their salience, i.e. ability to capture attentional focus, and valence. However, it is not known if interference by salience or valence is associated with self-reported adversity. In two independent study samples of healthy men (Study 1: n = 44; mean age [standard deviation (SD)] = 25.9 [3.4] years; Study 2: n = 37; 43.5 [9.7] years) we used the attention modulation task (AMT) that probed interference by two attention-modulating conditions, salience and valence separately across repeated target stimuli. The AMT measures the effects of visual distractors (pictures) on the performance of auditory discrimination tasks (target stimuli). We hypothesized that participants reporting higher levels of childhood adversity, measured with the childhood trauma questionnaire, would show sustained interference in trials with lower salience. Due to conflicting reports on the valence-modulation, we tested the valence condition in an exploratory manner. Linear mixed models revealed an interaction between reported childhood adversity and the salience condition across tone presentations in both study samples (Sample 1: p = .03; Sample 2: p = .04), while there were no effects for the valence condition across both studies. Our study suggests that higher self-reported childhood adversity is related to faster processing of target cues during high salience, but slower during low salience conditions. These results hint to the mechanisms linking childhood adversity and psychopathological symptoms in the attentional domain.
1000 Sacherschließung
lokal Salivary alpha-amylases
lokal Salience
lokal Adverse childhood experiences
lokal Hydrocortisone
lokal Interference
lokal Valence
lokal Attention
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/QW1lZGljaywgR3JldGE=|https://frl.publisso.de/adhoc/uri/S3J5bG92YSwgTWFyaW5h|https://frl.publisso.de/adhoc/uri/TWF5ZXIsIEthdGhyaW4=|https://frl.publisso.de/adhoc/uri/SXp5dXJvdiwgSWdvcg==|https://orcid.org/0000-0001-6205-6868|https://orcid.org/0000-0002-6172-274X|https://orcid.org/0000-0002-1456-091X|https://frl.publisso.de/adhoc/uri/SGVsbGVyLCBKb2hhbm5h|https://frl.publisso.de/adhoc/uri/TGksIE1lbmc=|https://orcid.org/0000-0003-2737-2691|https://orcid.org/0000-0002-0361-5559|https://orcid.org/0000-0001-5317-933X|https://orcid.org/0000-0001-7857-4483|https://orcid.org/0000-0002-8809-4034
1000 Label
1000 Förderer
  1. Interdisciplinary Center of Clinical Research of the Medical Faculty Jena (LC) |
  2. Deutsche Forschungsgemeinschaft |
  3. European Commission |
  4. Heel |
  5. Thüringer Universitäts- und Landesbibliothek Jena |
  6. Projekt DEAL |
1000 Fördernummer
  1. -
  2. SFB779/A06; 512648189
  3. -
  4. -
  5. -
  6. -
1000 Förderprogramm
  1. -
  2. -
  3. ERA-Net: Neuromarket
  4. -
  5. Open Access Publication Fund
  6. Open Access funding
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Interdisciplinary Center of Clinical Research of the Medical Faculty Jena (LC) |
    1000 Förderprogramm -
    1000 Fördernummer -
  2. 1000 joinedFunding-child
    1000 Förderer Deutsche Forschungsgemeinschaft |
    1000 Förderprogramm -
    1000 Fördernummer SFB779/A06; 512648189
  3. 1000 joinedFunding-child
    1000 Förderer European Commission |
    1000 Förderprogramm ERA-Net: Neuromarket
    1000 Fördernummer -
  4. 1000 joinedFunding-child
    1000 Förderer Heel |
    1000 Förderprogramm -
    1000 Fördernummer -
  5. 1000 joinedFunding-child
    1000 Förderer Thüringer Universitäts- und Landesbibliothek Jena |
    1000 Förderprogramm Open Access Publication Fund
    1000 Fördernummer -
  6. 1000 joinedFunding-child
    1000 Förderer Projekt DEAL |
    1000 Förderprogramm Open Access funding
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6475319.rdf
1000 Erstellt am 2024-04-22T10:59:36.502+0200
1000 Erstellt von 242
1000 beschreibt frl:6475319
1000 Bearbeitet von 317
1000 Zuletzt bearbeitet 2024-04-29T07:34:35.605+0200
1000 Objekt bearb. Mon Apr 29 07:34:05 CEST 2024
1000 Vgl. frl:6475319
1000 Oai Id
  1. oai:frl.publisso.de:frl:6475319 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

View source