Download
s13227-019-0142-5.pdf 13,04MB
WeightNameValue
1000 Titel
  • Cell cycle dynamics during diapause entry and exit in an annual killifish revealed by FUCCI technology
1000 Autor/in
  1. Dolfi, Luca |
  2. Ripa, Roberto |
  3. Antebi, Adam |
  4. Valenzano, Dario Riccardo |
  5. Cellerino, Alessandro |
1000 Erscheinungsjahr 2019
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2019-11-08
1000 Erschienen in
1000 Quellenangabe
  • 10(1):29
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2019
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s13227-019-0142-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842169/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!Annual killifishes are adapted to surviving and reproducing over alternating dry and wet seasons. During the dry season, all adults die and desiccation-resistant embryos remain encased in dry mud for months or years in a state of diapause where their development is halted in anticipation of the months that have to elapse before their habitats are flooded again. Embryonic development of annual killifishes deviates from canonical teleost development. Epiblast cells disperse during epiboly, and a 'dispersed phase' precedes gastrulation. In addition, annual fish have the ability to enter diapause and block embryonic development at the dispersed phase (diapause I), mid-somitogenesis (diapause II) and the final phase of development (diapause III). Developmental transitions associated with diapause entry and exit can be linked with cell cycle events. Here we set to image this transition in living embryos.!##!Results!#!To visibly explore cell cycle dynamics during killifish development in depth, we created a stable transgenic line in !##!Conclusions!#!Our study reveals surprising levels of coordination of cellular dynamics during diapause and provides a reference framework for further developmental analyses of this remarkable developmental quiescent state.
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/RG9sZmksIEx1Y2E=|https://frl.publisso.de/adhoc/uri/UmlwYSwgUm9iZXJ0bw==|https://frl.publisso.de/adhoc/uri/QW50ZWJpLCBBZGFt|https://frl.publisso.de/adhoc/uri/VmFsZW56YW5vLCBEYXJpbyBSaWNjYXJkbw==|https://orcid.org/0000-0003-3834-0097
1000 Label
1000 Förderer
  1. Scuola Normale Superiore |
1000 Fördernummer
  1. -
1000 Förderprogramm
  1. CellerinoSNS-17
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Scuola Normale Superiore |
    1000 Förderprogramm CellerinoSNS-17
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6475693.rdf
1000 Erstellt am 2024-05-08T10:06:23.528+0200
1000 Erstellt von 336
1000 beschreibt frl:6475693
1000 Bearbeitet von 317
1000 Zuletzt bearbeitet 2024-05-14T11:31:43.765+0200
1000 Objekt bearb. Tue May 14 11:31:33 CEST 2024
1000 Vgl. frl:6475693
1000 Oai Id
  1. oai:frl.publisso.de:frl:6475693 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

View source