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10.1186_s40463-023-00646-5.pdf 1,51MB
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1000 Titel
  • Functional outcome following intracapsular resection of head and neck peripheral nerve sheath tumors: A retrospective cohort
1000 Autor/in
  1. Kampel, Liyona |
  2. Serafimova, Marga |
  3. Edalati, Shaun |
  4. Brenner, Adi |
  5. Masarwy, Razan |
  6. Warshavsky, Anton |
  7. Horowitz, Gilad |
  8. Shapira, Yuval |
  9. Muhanna, Nidal |
1000 Erscheinungsjahr 2023
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2023-10-01
1000 Erschienen in
1000 Quellenangabe
  • 52(1)
1000 Copyrightjahr
  • 2023
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s40463-023-00646-5 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10546627/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:sec><jats:title>Background</jats:title><jats:p> Intracapsular resection of head and neck peripheral nerve sheath tumors (PNST) has emerged as a nerve-preserving technique compared to en bloc resection. The aim of this study was to evaluate and compare the functional outcome of both surgical techniques performed at a single tertiary referral center. </jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p> This is a retrospective cohort of patients with head and neck PNST undergoing surgical resection from 2011 to 2021 at the Tel Aviv Sourasky Medical Center. Demographic data, the nerve of origin and surgical technique, including the use of intraoperative nerve monitoring were recorded and analyzed in association with postoperative functional outcomes. </jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p> Overall, 25 patients who had a cervical or parapharyngeal PNST resected were included. Nerve function was preserved in 11 of 18 patients (61%) who underwent intracapsular resection, while all those who underwent en bloc resections inevitably suffered from neurologic deficits (100%, N = 7). Sympathetic chain origin and an apparent neurologic deficit pre-operatively were associated with postoperative neural compromise. </jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p> Improved functional outcome can be anticipated following intracapsular resection of extracranial head and neck PNST compared to complete resection, particularly in asymptomatic patients. </jats:p></jats:sec><jats:sec><jats:title>Graphical Abstract</jats:title><jats:p> </jats:p></jats:sec>
1000 Sacherschließung
lokal Humans [MeSH]
lokal Neck/surgery [MeSH]
lokal Intracapsular resection
lokal Treatment Outcome [MeSH]
lokal Original Research Article
lokal Retrospective Studies [MeSH]
lokal Head [MeSH]
lokal Peripheral nerve sheath tumor
lokal Intraoperative nerve monitoring
lokal Schwannoma
lokal Nerve Sheath Neoplasms/surgery [MeSH]
lokal Head and Neck Neoplasms/surgery [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/S2FtcGVsLCBMaXlvbmE=|https://frl.publisso.de/adhoc/uri/U2VyYWZpbW92YSwgTWFyZ2E=|https://frl.publisso.de/adhoc/uri/RWRhbGF0aSwgU2hhdW4=|https://frl.publisso.de/adhoc/uri/QnJlbm5lciwgQWRp|https://frl.publisso.de/adhoc/uri/TWFzYXJ3eSwgUmF6YW4=|https://frl.publisso.de/adhoc/uri/V2Fyc2hhdnNreSwgQW50b24=|https://frl.publisso.de/adhoc/uri/SG9yb3dpdHosIEdpbGFk|https://frl.publisso.de/adhoc/uri/U2hhcGlyYSwgWXV2YWw=|https://frl.publisso.de/adhoc/uri/TXVoYW5uYSwgTmlkYWw=
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1000 Erstellt am 2024-05-14T08:16:20.373+0200
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