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1000 Titel
  • The Non-linear Relationship Between Normal Range Systolic Blood Pressure and Cardiovascular or All-Cause Mortality Among Elderly Population
1000 Autor/in
  1. Sun, Shuo |
  2. Liu, Xiao-cong |
  3. He, Guo-dong |
  4. Lo, Kenneth |
  5. Feng, Ying-qing |
  6. Huang, Yu-qing |
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-07-27
1000 Erschienen in
1000 Quellenangabe
  • 8:677189
1000 Copyrightjahr
  • 2021
1000 Embargo
  • 2022-01-29
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.3389/fcvm.2021.677189 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8353072/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Abstract/Summary
  • <jats:p><jats:bold>Purpose:</jats:bold> The aim was to explore the association of normal range SBP with cardiovascular and all-cause mortality in older adults without hypertension.</jats:p><jats:p><jats:bold>Methods:</jats:bold> Participants aged ≥ 65 years without hypertension and those had an SBP level between 90 and 129 mmHg were included from the National Health and Nutrition Examination Survey (1999–2014). SBP was categorized into: 90–99, 100–109, 110–119, and 120–129 mmHg. Multivariate Cox regression was performed with hazard ratio (HR) and 95% confidence interval (CI).</jats:p><jats:p><jats:bold>Results:</jats:bold> Of the 1,074 participants, 584 were men (54.38%). Compared with participants with SBP level ranged 110 to 119 mmHg, the HRs for all-cause mortality risk was 1.83 (95% CI: 1.04, 3.23) for SBP level ranged 90 to 99 mm Hg, 0.87 (95% CI: 0.54, 1.41) for SBP level ranged 100 to 109 mmHg, and 1.30 (95% CI: 0.96, 1.75) for SBP level ranged 120 to 129 mmHg (P for trend = 0.448), and the HR for cardiovascular mortality risk was 3.30 (95% CI: 0.87, 12.54) for SBP level ranged 90 to 99 mmHg, 0.35(95% CI: 0.08, 1.56) for SBP level ranged 100 to 109 mmHg, and 1.75 (95% CI: 0.78, 3.94) for SBP level ranged 120 to 129 mm Hg (P for trend = 0.349) after confounders were adjusted.</jats:p><jats:p><jats:bold>Conclusion:</jats:bold> These were a nonlinear association of normal range SBP level with all-cause and cardiovascular death in older adults.</jats:p>
1000 Sacherschließung
lokal all-cause mortality
lokal systolic blood pressure
lokal cardiovascular mortality
lokal normal blood pressure
lokal elderly population
lokal Cardiovascular Medicine
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