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10.1186_s40463-023-00643-8.pdf 1,34MB
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1000 Titel
  • Do patients regret having in-office vocal fold injections for glottic insufficiency?
1000 Autor/in
  1. Liu, Alice |
  2. Ji, Yunqi |
  3. Hu, Amanda |
1000 Erscheinungsjahr 2023
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2023-01-01
1000 Erschienen in
1000 Quellenangabe
  • 52(1)
1000 Copyrightjahr
  • 2023
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s40463-023-00643-8 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10129306/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:sec><jats:title>Background</jats:title><jats:p> In-office vocal fold injections (VFI) are an effective treatment for glottic insufficiency. The primary objective of this study was to assess if patients reported decisional regret after VFI. Secondary objectives included determining if variables were associated with lower decisional regret. </jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p> Case–control study of patients who underwent in-office VFIs for glottic insufficiency from August 2017 to December 2019 at a tertiary laryngology clinic. Participants completed the validated Decision Regret Scale (DRS). Demographic data, clinician's perceptual analysis with GRBAS (Grade, Roughness, Breathiness, Asthenia, Strain), and patient's self-reported Voice Handicap Index-10 (VHI-10) were analyzed. Nonparametric tests as well as univariate and multiple logistics regression were performed. </jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p> Of patients eligible, 75% (136/182) completed the DRS (mean age 65.4 years (SD 13.9), 58.1% male). Eighty-three (61.0%) reported no decisional regret, thirty-three (24.3%) reported mild decisional regret, and twenty (14.7%) reported moderate to strong decisional regret. Improvement in most recent VHI-10 (Kendall correlation coefficient tau = 0.156, p = 0.029), Grade of voice (tau = 0.236, p value = 0.002) and Breathiness of voice (tau = 0.150, p = 0.044) were associated with lower DRS. Multivariate logistics regression results showed that the change in Grade of voice (OR 9.9, p &lt; 0.01), Roughness (OR 0.2, p &lt; 0.01) and Breathiness (OR 0.2, p &lt; 0.03) were significantly associated with DRS. </jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p> The majority of patients had no or mild decisional regret after in-office VFI for glottic insufficiency. Both patients who reported less vocal handicap after VFI and clinician-noted improvements in perceptual evaluation of voice after VFI were associated with significantly lower decisional regret. </jats:p></jats:sec><jats:sec><jats:title>Graphical Abstract</jats:title><jats:p> </jats:p></jats:sec>
1000 Sacherschließung
lokal Decision regret scale
lokal Female [MeSH]
lokal Voice handicap index
lokal Aged [MeSH]
lokal Humans [MeSH]
lokal Vocal fold injections
lokal Treatment Outcome [MeSH]
lokal Retrospective Studies [MeSH]
lokal Vocal fold paralysis
lokal Vocal Cords [MeSH]
lokal Male [MeSH]
lokal Patient reported outcomes
lokal Larynx [MeSH]
lokal Case-Control Studies [MeSH]
lokal Original Research Article
lokal Injections [MeSH]
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0003-4813-836X|https://frl.publisso.de/adhoc/uri/SmksIFl1bnFp|https://frl.publisso.de/adhoc/uri/SHUsIEFtYW5kYQ==
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