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10.1186_s40463-021-00554-6.pdf 1,17MB
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1000 Titel
  • Intracranial otogenic complications in adults: New factors that influenced its onset, frequency and nature
1000 Autor/in
  1. Wierzbicka, Małgorzata |
  2. Staśkiewicz, Michalina |
  3. Rosiak, Oskar |
  4. Karmelita-Katulska, Katarzyna |
  5. Szyfter, Witold |
  6. Gawęcki, Wojciech |
1000 Erscheinungsjahr 2022
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2022-01-01
1000 Erschienen in
1000 Quellenangabe
  • 51(1)
1000 Copyrightjahr
  • 2022
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s40463-021-00554-6 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8894544/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:sec><jats:title>Background</jats:title><jats:p> To compare the clinical features of two time cohorts of patients: “pre-COVID-19” and “COVID-19”—admitted as emergency with intracranial otogenic complications, with special regard to sigmoid sinus thrombosis (CVST). </jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p> Retrospective analysis of patients documentation concerning urgent procedures of intracranial otogenic complications at tertiary-referral otolaryngology department. Analysed database—pre-COVID-19 cohort (January–February 2019/2020): 1434 otological outpatient visits, 509 planned otosurgeries and 17 urgent otological procedures; COVID-19 cohort (March–April 2020/2021): 1150, 566 and 20 respectively. Overall intracranial complications: 5 and 9 respectively. Analysed outcome measures: incidence proportion of otogenic intracranial complications in relation to planned and urgent otosurgical procedures; incidence proportion of intracranial complications in relation to the total number of emergency and planned outpatient consultations and the total number of planned surgical procedures. </jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p> There were 14 intracranial complications, 5 in the pre-COVID and 9 in the COVID cohort, including 1 and 5 sigmoid sinus thrombosis, respectively. Out of them, 3 and 5 patients reported a prior history of chronic otitis media, respectively. In COVID period, CVST was more prevalent, with 2 cases (22.2%) presenting solitary CVST, and 3 cases (33.3%) CVST and a simultaneous brain abscess or meningitis. CVST was much more frequent in the COVID period (p &lt; 0.01). </jats:p></jats:sec><jats:sec><jats:title>Conclusions</jats:title><jats:p> Despite the published data which suggest that CVST is a rare event associated with COVID-19 infection, based on our experience, CVST can be expected as a frequent component of intracranial otogenic complications during COVID-19 pandemic time. Trial registration This research study was conducted retrospectively from data obtained for clinical purposes. We consulted extensively with the Bioethics Committee at Poznan University of Medical Sciences who determined that our study did not need ethical approval. An official waiver of ethical approval was granted from the Bioethics Committee at Poznan University of Medical Sciences. </jats:p></jats:sec><jats:sec><jats:title>Graphical Abstract</jats:title><jats:p> </jats:p></jats:sec>
1000 Sacherschließung
lokal Sinus Thrombosis, Intracranial/epidemiology [MeSH]
gnd 1206347392 COVID-19
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Sinus Thrombosis, Intracranial/etiology [MeSH]
lokal Otogenic complication
lokal Retrospective Studies [MeSH]
lokal COVID-19
lokal COVID-19/complications [MeSH]
lokal Pandemics [MeSH]
lokal Sigmoid sinus thrombosis
lokal Original Research Article
lokal COVID-19/epidemiology [MeSH]
lokal SARS-CoV-2 [MeSH]
lokal SARS-CoV-2
lokal Cerebral venous thrombosis
lokal Latent otitis media
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0003-0006-6352|https://orcid.org/0000-0003-0190-2359|https://orcid.org/0000-0002-5326-4777|https://frl.publisso.de/adhoc/uri/S2FybWVsaXRhLUthdHVsc2thLCBLYXRhcnp5bmE=|https://orcid.org/0000-0001-7870-1964|https://orcid.org/0000-0002-6174-9758
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1000 Erstellt am 2024-05-14T13:37:44.577+0200
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