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10.1186_s40463-021-00551-9.pdf 1,04MB
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1000 Titel
  • Contralateral nodal failures in oropharyngeal cancers after TORS and unilateral neck management: A retrospective study
1000 Autor/in
  1. Sahovaler, Axel |
  2. Lee, John J. W. |
  3. Xu, Wei |
  4. Su, Susie |
  5. Hosni, Ali |
  6. Bayley, Andrew |
  7. Goldstein, David P. |
  8. de Almeida, John |
1000 Verlag
  • SAGE Publications
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-01-01
1000 Erschienen in
1000 Quellenangabe
  • 50(1):71
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s40463-021-00551-9 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8697460/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>Report the incidence of contralateral nodal failure rates in well-lateralized oropharyngeal carcinoma treated with upfront surgery and unilateral neck management.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>Lateralized oropharyngeal carcinomas treated with upfront surgery using transoral robotic surgery (TORS) and unilateral neck management (unilateral neck dissection ± unilateral radiation treatment) were identified. Primary endpoint was contralateral regional control (CRC). Secondary endpoints were local control (LC), and overall survival (OS).</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>Thirty-two patients were included. Pathologic T categories included 66% pT1, 31% pT2 and 3% pT3. Nodal diseases comprised 41% N0 and 47% N1 (AJCC 8th). Twenty-three (72%) patients had HPV related tumors. 3-years CRC, LC and OS were 100%, 96% (89–100) and 96% (CI 89–100). One patient developed a second primary with contralateral nodal disease. Only one patient died from another primary cancer.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>In selected patients with lateralized oropharyngeal cancer, treatment with TORS and ipsilateral management of the neck may be oncologically safe without significant risk of contralateral failure.</jats:p> <jats:p><jats:italic>Level of evidence</jats:italic>: Level 2.</jats:p> </jats:sec><jats:sec> <jats:title>Graphical abstract</jats:title> </jats:sec>
1000 Sacherschließung
lokal Carcinoma, Squamous Cell/surgery [MeSH]
lokal Neck Dissection [MeSH]
lokal Humans [MeSH]
lokal Oropharyngeal cancer
lokal TORS
lokal Robotic Surgical Procedures [MeSH]
lokal Original Research Article
lokal Retrospective Studies [MeSH]
lokal Contralateral nodal failure
lokal Oropharyngeal Neoplasms/surgery [MeSH]
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/U2Fob3ZhbGVyLCBBeGVs|https://frl.publisso.de/adhoc/uri/TGVlLCBKb2huIEouIFcu|https://frl.publisso.de/adhoc/uri/WHUsIFdlaQ==|https://frl.publisso.de/adhoc/uri/U3UsIFN1c2ll|https://frl.publisso.de/adhoc/uri/SG9zbmksIEFsaQ==|https://frl.publisso.de/adhoc/uri/QmF5bGV5LCBBbmRyZXc=|https://frl.publisso.de/adhoc/uri/R29sZHN0ZWluLCBEYXZpZCBQLg==|https://orcid.org/0000-0002-1546-5033
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1000 Erstellt am 2024-05-17T11:11:41.263+0200
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