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10.1186_s40463-019-0338-7.pdf 548,36KB
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1000 Titel
  • The role of repeat fine needle aspiration in managing indeterminate thyroid nodules
1000 Autor/in
  1. Allen, Laura |
  2. Al Afif, Ayham |
  3. Rigby, Matthew H. |
  4. Bullock, Martin J. |
  5. Trites, Jonathan |
  6. Taylor, S. Mark |
  7. Hart, Robert D. |
1000 Verlag
  • SAGE Publications
1000 Erscheinungsjahr 2019
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2019-01-01
1000 Erschienen in
1000 Quellenangabe
  • 48(1):16
1000 Copyrightjahr
  • 2019
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s40463-019-0338-7 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425601/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Background!#!The Bethesda System is the most widely used for reporting fine needle aspiration (FNA) cytology. It recommends a repeat FNA (rFNA) when initial results are category I or III. It is unclear how often rFNA provides additional diagnostic information. We sought to investigate its utility at our institution.!##!Methods!#!A retrospective chart review was performed of patients who had a category I or III FNA result and underwent rFNA of the same thyroid nodule between 2013 and 2015 at the QE II Health Sciences Centre in Nova Scotia, Canada. Results of initial FNA and ultrasound characteristics, rFNA, demographic data, surgical details, and pathology were collected.!##!Results!#!A total of 237 patients (474 thyroid FNAs) were included. Most initial FNAs were category I (82%), the remainder category III (18%). rFNA yielded a different category 60% of the time. However, 60% remained category I or III. rFNA results of benign or malignant were found in 40% of cases; 1% were SFN/SFM. Twenty-seven percent of patients had surgery after rFNA; of those 68% had category I or III rFNA results. Of all nodules that underwent surgery, 46% were malignant, including 32% with category I rFNA results, and 42% category III.!##!Conclusions!#!rFNA for category I and III nodules provided a definitive diagnosis in only 40% of cases, which is important for patient counseling. Malignancy rates at our centre were higher for these categories than predicted by Bethesda. Clinical management should consider institution specific malignancy rates, patient factors, and ultrasound findings.
1000 Sacherschließung
lokal Thyroid Nodule/surgery [MeSH]
lokal Thyroid Nodule/pathology [MeSH]
lokal Female [MeSH]
lokal Aged, 80 and over [MeSH]
lokal Aged [MeSH]
lokal Adult [MeSH]
lokal Biopsy, Fine-Needle [MeSH]
lokal Humans [MeSH]
lokal Predictive Value of Tests [MeSH]
lokal Retrospective Studies [MeSH]
lokal Thyroid nodule
lokal Middle Aged [MeSH]
lokal Bethesda system
lokal Thyroid
lokal FNA
lokal Reoperation [MeSH]
lokal Male [MeSH]
lokal Young Adult [MeSH]
lokal Original Research Article
lokal Thyroid Nodule/diagnostic imaging [MeSH]
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1000 Erstellt am 2024-05-21T09:05:00.555+0200
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