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1000 Titel
  • Metagenomic Next-Generation Sequencing Can Clinch Diagnosis of Non-Tuberculous Mycobacterial Infections: A Case Report
1000 Autor/in
  1. Zhu, He |
  2. Zhu, Min |
  3. Lei, Jia-Hui |
  4. Xiao, Ya-Li |
  5. Zhao, Li-Min |
1000 Verlag
  • Frontiers Media S.A.
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-07-26
1000 Erschienen in
1000 Quellenangabe
  • 8:679755
1000 Copyrightjahr
  • 2021
1000 Embargo
  • 2022-01-28
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.3389/fmed.2021.679755 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8350026/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Abstract/Summary
  • <jats:p>Non-tuberculou <jats:italic>Mycobacteria</jats:italic> (NTM) is ubiquitous in the environment and is conditional pathogen. Due to NTM and <jats:italic>Mycobacterium tuberculosis</jats:italic> belong to the genus <jats:italic>Mycobacterium</jats:italic>, their pathogenic mechanisms and clinical manifestations are similar. Therefore, NTM can cause tuberculosis-like lesions and lead to misdiagnosis. Early diagnosis and treatment greatly improve prognosis. However, traditional pathogenic microorganism detection has limitations, and it is difficult to accurately identify strains in clinical practice. Here, we report a 65-year-old man with NTM who presented with recurrent fever and cough. Computed tomography of the chest revealed a lung infection. The previous improper diagnosis and treatment did not improve his condition. With the aid of metagenomic next-generation sequencing, the pathogen was identified as <jats:italic>Mycobacterium avium complex</jats:italic>. Subsequently, he received accurate treatment and made significant improvements in clinical and radiology.</jats:p>
1000 Sacherschließung
lokal Medicine
lokal metagenomic next-generation sequencing
lokal non-tuberculous mycobacteria
lokal case report
lokal diagnosis
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/Wmh1LCBIZQ==|https://frl.publisso.de/adhoc/uri/Wmh1LCBNaW4=|https://frl.publisso.de/adhoc/uri/TGVpLCBKaWEtSHVp|https://frl.publisso.de/adhoc/uri/WGlhbywgWWEtTGk=|https://frl.publisso.de/adhoc/uri/WmhhbywgTGktTWlu
1000 Hinweis
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1000 @id frl:6477774.rdf
1000 Erstellt am 2024-05-21T10:47:53.790+0200
1000 Erstellt von 322
1000 beschreibt frl:6477774
1000 Zuletzt bearbeitet 2024-05-22T09:04:20.724+0200
1000 Objekt bearb. Wed May 22 09:04:20 CEST 2024
1000 Vgl. frl:6477774
1000 Oai Id
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