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1000
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Abstract/Summary
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<jats:title>Abstract</jats:title><jats:sec>
<jats:title>Background</jats:title>
<jats:p>The study aimed to evaluate the anatomical differences between positional and non-positional OSA, and to identify the potential predictors for distinguishing between these two types of OSA.</jats:p>
</jats:sec><jats:sec>
<jats:title>Methods</jats:title>
<jats:p>A cross-sectional study of 230 consecutive patients with OSA undergoing DISE (Drug-induced Sleep Endoscopy) was carried out at a tertiary academic medical center. The factors correlating with positional and non-positional OSA were analyzed, including clinical characteristics, polysomnography data, and DISE findings.</jats:p>
</jats:sec><jats:sec>
<jats:title>Results</jats:title>
<jats:p>Univariate analysis revealed that non-positional dependency was correlated with a higher BMI (<jats:italic>p</jats:italic> < 0.001), neck circumference (<jats:italic>p</jats:italic> < 0.001), modified Mallampati score (<jats:italic>p</jats:italic> = 0.003), AHI (<jats:italic>p</jats:italic> < 0.001), degree of velum concentric collapse (<jats:italic>p</jats:italic> = 0.004), degree of oropharyngeal lateral wall collapse (<jats:italic>p</jats:italic> < 0.001), and degree of tongue base anteroposterior collapse (<jats:italic>p</jats:italic> = 0.004). Multivariate analysis revealed that oropharyngeal lateral wall collapse (OR = 1.90, <jats:italic>p</jats:italic> = 0.027) was the only anatomical factor significantly predicted non-positional dependency in OSA patients. AHI (OR = 1.04, <jats:italic>p</jats:italic> < 0.001), although significant, made only a marginal contribution to the prediction of non-positional dependency.</jats:p>
</jats:sec><jats:sec>
<jats:title>Conclusions</jats:title>
<jats:p>Oropharyngeal lateral wall collapse was identified as the only anatomical predictor for non-positional dependency in OSA patients. Therefore, further treatment modalities should address the distinct anatomical trait between positional and non-positional OSA.</jats:p>
</jats:sec><jats:sec>
<jats:title>Graphical abstract</jats:title>
</jats:sec>
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1000
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Hinweis
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DeepGreen-ID: 0a84fb6db04848b6a0252d5e808d976f ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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