A case report of severe nasal ischemia from cold agglutinin disease and a novel treatment protocol including HBOT

  1. Kohlert, Scott ORCID logo
  2. McLean, Laurie
  3. Scarvelis, Dimitrios
  4. Thompson, Calvin

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10.1186_s40463-019-0369-0.pdf 1,16MB
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1000 Titel
  • A case report of severe nasal ischemia from cold agglutinin disease and a novel treatment protocol including HBOT
1000 Autor/in
  1. Kohlert, Scott |
  2. McLean, Laurie |
  3. Scarvelis, Dimitrios |
  4. Thompson, Calvin |
1000 Verlag
  • SAGE Publications
1000 Erscheinungsjahr 2019
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2019-01-01
1000 Erschienen in
1000 Quellenangabe
  • 48(1)
1000 Copyrightjahr
  • 2019
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s40463-019-0369-0 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6805523/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:p> Cold agglutinin disease (CAD) is a rare condition leading to blood agglutination and autoimmune hemolytic anemia. Cutaneous ischemia resulting from CAD in the head and neck is uncommon. Treatment regimens and outcomes vary widely in the literature and no clear protocol exists. This manuscript describes a patient with CAD who developed severe ischemia of the nose that resolved completely without sequellae following a medical regimen of aspirin, low molecular weight heparin, nitroglycerin ointment and hyperbaric oxygen therapy (HBOT). To our knowledge, this is the first reported case where nitroglycerin ointment or HBOT was successfully employed in the treatment of this complication. </jats:p>
1000 Sacherschließung
lokal Female [MeSH]
lokal Ischemia/therapy [MeSH]
lokal Aged, 80 and over [MeSH]
lokal Hyperbaric Oxygenation [MeSH]
lokal Nasal ischemia
lokal Humans [MeSH]
lokal Ischemia/drug therapy [MeSH]
lokal Cold agglutinin disease
lokal Hyperbaric oxygen
lokal Nose/blood supply [MeSH]
lokal Nitroglycerin/administration
lokal Ointments [MeSH]
lokal Ischemia/etiology [MeSH]
lokal Anticoagulants/therapeutic use [MeSH]
lokal Acrocyanosis
lokal Vasodilator Agents/administration
lokal Combined Modality Therapy [MeSH]
lokal Anemia, Hemolytic, Autoimmune/complications [MeSH]
lokal Administration, Topical [MeSH]
lokal Enoxaparin/administration
lokal Case Report
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0003-1814-0776|https://frl.publisso.de/adhoc/uri/TWNMZWFuLCBMYXVyaWU=|https://frl.publisso.de/adhoc/uri/U2NhcnZlbGlzLCBEaW1pdHJpb3M=|https://frl.publisso.de/adhoc/uri/VGhvbXBzb24sIENhbHZpbg==
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