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1000 Titel
  • Development of a pediatric obstructive sleep apnea triage algorithm
1000 Autor/in
  1. Heath, D. S. |
  2. El-Hakim, H. |
  3. Al-Rahji, Y. |
  4. Eksteen, E. |
  5. Uwiera, T. C. |
  6. Isaac, A. |
  7. Castro-Codesal, M. |
  8. Gerdung, C. |
  9. Maclean, J. |
  10. Mandhane, Piush |
1000 Verlag
  • SAGE Publications
1000 Erscheinungsjahr 2021
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2021-01-01
1000 Erschienen in
1000 Quellenangabe
  • 50(1):48
1000 Copyrightjahr
  • 2021
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s40463-021-00528-8 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8281470/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Introduction</jats:title> <jats:p>Diagnosis and treatment of obstructive sleep apnea (OSA) in children is often delayed due to the high prevalence and limited physician and sleep testing resources. As a result, children may be referred to multiple specialties, such as pediatric sleep medicine and pediatric otolaryngology, resulting in long waitlists.</jats:p> </jats:sec><jats:sec> <jats:title>Method</jats:title> <jats:p>We used data from our pediatric OSA clinic to identify predictors of tonsillectomy and/or adenoidectomy (AT). Before being seen in the clinic, parents completed the Pediatric Sleep Questionnaire (PSQ) and screening questionnaires for restless leg syndrome (RLS), nasal rhinitis, and gastroesophageal reflux disease (GERD). Tonsil size data were obtained from patient charts and graded using the Brodsky-five grade scale. Children completed an overnight oximetry study before being seen in the clinic, and a McGill oximetry score (MOS) was assigned based on the number and depth of oxygen desaturations. Logistic regression, controlling for otolaryngology physician, was used to identify significant predictors of AT. Three triage algorithms were subsequently generated based on the univariate and multivariate results to predict AT.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>From the OSA cohort, there were 469 eligible children (47% female, mean age = 8.19 years, <jats:italic>SD</jats:italic> = 3.59), with 89% of children reported snoring. Significant predictors of AT in univariate analysis included tonsil size and four PSQ questions, (1) struggles to breathe at night, (2) apneas, (3) daytime mouth breathing, and (4) AM dry mouth. The first triage algorithm, only using the four PSQ questions, had an odds ratio (OR) of 4.02 for predicting AT (sensitivity = 0.28, specificity = 0.91). Using only tonsil size, the second algorithm had an OR to predict AT of 9.11 (sensitivity = 0.72, specificity = 0.78). The third algorithm, where MOS was used to stratify risk for AT among those children with 2+ tonsils, had the same OR, sensitivity, and specificity as the tonsil-only algorithm.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>Tonsil size was the strongest predictor of AT, while oximetry helped stratify individual risk for AT. We recommend that referral letters for snoring children include graded tonsil size to aid in the triage based on our findings. Children with 2+ tonsil sizes should be triaged to otolaryngology, while the remainder should be referred to a pediatric sleep specialist.</jats:p> </jats:sec><jats:sec> <jats:title>Graphical abstract</jats:title> </jats:sec>
1000 Sacherschließung
lokal Algorithms [MeSH]
lokal Female [MeSH]
lokal Adenoidectomy
lokal Sleep Apnea, Obstructive/diagnosis [MeSH]
lokal Oximetry
lokal Sleep-related breathing disorder
lokal Tonsillectomy
lokal Adenoidectomy [MeSH]
lokal Humans [MeSH]
lokal Sleep Apnea, Obstructive/surgery [MeSH]
lokal Snoring
lokal Male [MeSH]
lokal Tonsillectomy [MeSH]
lokal Triage [MeSH]
lokal Child [MeSH]
lokal Obstructive sleep apnea
lokal Short Report
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/SGVhdGgsIEQuIFMu|https://frl.publisso.de/adhoc/uri/RWwtSGFraW0sIEgu|https://frl.publisso.de/adhoc/uri/QWwtUmFoamksIFku|https://frl.publisso.de/adhoc/uri/RWtzdGVlbiwgRS4=|https://frl.publisso.de/adhoc/uri/VXdpZXJhLCBULiBDLg==|https://frl.publisso.de/adhoc/uri/SXNhYWMsIEEu|https://frl.publisso.de/adhoc/uri/Q2FzdHJvLUNvZGVzYWwsIE0u|https://frl.publisso.de/adhoc/uri/R2VyZHVuZywgQy4=|https://frl.publisso.de/adhoc/uri/TWFjbGVhbiwgSi4=|https://orcid.org/0000-0003-3682-9120
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1000 Erstellt am 2024-05-21T20:30:40.787+0200
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