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10.1186_s40463-023-00682-1.pdf 770,22KB
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1000 Titel
  • Quantifying Surgical Completeness in Patients with Aspirin Exacerbated Respiratory Disease
1000 Autor/in
  1. Levin, Marc |
  2. Chan, Yvonne |
  3. Sommer, Doron D. |
  4. Thamboo, Andrew |
  5. Lee, John M. |
1000 Verlag
  • SAGE Publications
1000 Erscheinungsjahr 2023
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2023-12-01
1000 Erschienen in
1000 Quellenangabe
  • 52(1)
1000 Copyrightjahr
  • 2023
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s40463-023-00682-1 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10726574/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:sec><jats:title>Background</jats:title><jats:p> Aspirin exacerbated respiratory disease (AERD) in patients who have had sinus surgery remains a management challenge. Aspirin desensitization and biologics are additional treatment options. It remains unclear if patients require a more comprehensive surgery prior to implementing such additional therapies. The purpose of this study was to quantify prior surgery completeness in AERD patients at a tertiary rhinology practice. </jats:p></jats:sec><jats:sec><jats:title>Methods</jats:title><jats:p> Paranasal sinus CT scans were reviewed by four academic rhinologists to assess surgery completeness. Using a published CT grading system, each sinus was graded on the completeness of surgery and middle turbinate reduction. A score out of 14 was calculated for each patient (7 per side). </jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p> Sixty-one patients with AERD out of 141 available were included. Mean inter-rater agreement across all sinuses was moderate (k = 0.42). The mean completeness score was 6.7/14. The following procedures were rated as complete (means): uncinectomy (L: 84%, R: 82%, k = 0.44), maxillary (L: 83%, R: 77%, k = 0.32), middle turbinate reduction (L: 45%, R: 46%, k = 0.31), anterior ethmoid (L: 35%, R: 39%, k = 0.51), sphenoid (L: 36%, R: 35%, k = 0.4), posterior ethmoid (L: 30%, R: 30%, k = 0.48), frontal (L: 22%, R: 21%, k = 0.46). </jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p> Prior surgery in AERD patients were mostly deemed incomplete. Uncinectomy and maxillary antrostomy are the most common procedures previously performed. It remains toe seen whether this would be considered ‘adequate’ surgery or more ‘complete’ surgery is required to achieve greater disease control. </jats:p></jats:sec>
1000 Sacherschließung
lokal Surgical completeness
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Nasal Polyps/surgery [MeSH]
lokal Chronic rhinosinusitis
lokal Rhinitis/surgery [MeSH]
lokal Endoscopy [MeSH]
lokal endoscopic sinus surgery
lokal Aspirin/adverse effects [MeSH]
lokal Chronic Disease [MeSH]
lokal Original Research Article
lokal Sinusitis/surgery [MeSH]
lokal Asthma, Aspirin-Induced [MeSH]
lokal Aspirin exacerbated respiratory disease
lokal CT scan
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-2345-5222|https://frl.publisso.de/adhoc/uri/Q2hhbiwgWXZvbm5l|https://frl.publisso.de/adhoc/uri/U29tbWVyLCBEb3JvbiBELg==|https://frl.publisso.de/adhoc/uri/VGhhbWJvbywgQW5kcmV3|https://frl.publisso.de/adhoc/uri/TGVlLCBKb2huIE0u
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1000 Erstellt am 2024-05-21T22:48:47.998+0200
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