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1000
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Abstract/Summary
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<jats:p>Mitogen-activated protein kinase (MAPK) cascades are fundamental signal transduction modules in all eukaryotic organisms, participating growth and development, as well as stress response. In the present study, three MAPK genes were successfully identified from the genome of <jats:italic>Chlamys farreri</jats:italic>, respectively, named <jats:italic>CfERK1/2</jats:italic>, <jats:italic>CfJNK</jats:italic>, and <jats:italic>Cfp38</jats:italic>, and only one copy of <jats:italic>ERK</jats:italic>, <jats:italic>JNK</jats:italic>, and <jats:italic>p38</jats:italic> were detected. Domain analysis indicated that <jats:italic>CfMAPK</jats:italic>s possessed the typical domains, including S_TKc, Pkinase, and PKc_like domain. Phylogenetic analysis showed that three <jats:italic>CfMAPK</jats:italic>s of MAPK subfamilies exists in the common ancestor of vertebrates and invertebrates. All <jats:italic>CfMAPK</jats:italic>s specifically expressed during larval development and in adult tissues, and the expression level of <jats:italic>CfERK1/2</jats:italic> and <jats:italic>Cfp38</jats:italic> was apparently higher than that of <jats:italic>CfJNK</jats:italic>. Under heat stress, the expression of <jats:italic>CfERK1/2</jats:italic> and <jats:italic>Cfp38</jats:italic> were significantly downregulated and then upregulated in four tissues, while the expression of <jats:italic>CfJNK</jats:italic> increased in all tissues; these different expression patterns suggested a different molecular mechanism of <jats:italic>CfMAPKs</jats:italic> for bivalves to adapt to temperature changes. The diversity of <jats:italic>CfMAPKs</jats:italic> and their specific expression patterns provide valuable information for better understanding of the functions of MAPK cascades in bivalves.</jats:p>
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1000
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Hinweis
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DeepGreen-ID: 89d9e0b7f80948f0acf981a3aad4bd25 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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