The admixed brushtail possum genome reveals invasion history in New Zealand and novel imprinted genes

  1. Bond, Donna ORCID logo
  2. Ortega-Recalde, Oscar
  3. Laird, Melanie K.
  4. Hayakawa, Takashi ORCID logo
  5. Richardson, Kyle S.
  6. Reese, Finlay ORCID logo
  7. Kyle, Bruce
  8. McIsaac-Williams, Brooke E.
  9. Robertson, Bruce ORCID logo
  10. van Heezik, Yolanda
  11. Adams, Amy L.
  12. Chang, Wei-Shan ORCID logo
  13. Haase, Bettina
  14. Mountcastle, Jacquelyn
  15. Driller, Maximilian
  16. Collins, Joanna
  17. Howe, Kerstin ORCID logo
  18. Go, Yasuhiro ORCID logo
  19. Thibaud-Nissen, Françoise ORCID logo
  20. Lister, Nicholas C.
  21. Waters, Paul ORCID logo
  22. Fedrigo, Olivier
  23. Jarvis, Erich D.
  24. Gemmell, Neil ORCID logo
  25. Alexander, Alana ORCID logo
  26. Hore, Timothy ORCID logo

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1000 Titel
  • The admixed brushtail possum genome reveals invasion history in New Zealand and novel imprinted genes
1000 Autor/in
  1. Bond, Donna |
  2. Ortega-Recalde, Oscar |
  3. Laird, Melanie K. |
  4. Hayakawa, Takashi |
  5. Richardson, Kyle S. |
  6. Reese, Finlay |
  7. Kyle, Bruce |
  8. McIsaac-Williams, Brooke E. |
  9. Robertson, Bruce |
  10. van Heezik, Yolanda |
  11. Adams, Amy L. |
  12. Chang, Wei-Shan |
  13. Haase, Bettina |
  14. Mountcastle, Jacquelyn |
  15. Driller, Maximilian |
  16. Collins, Joanna |
  17. Howe, Kerstin |
  18. Go, Yasuhiro |
  19. Thibaud-Nissen, Françoise |
  20. Lister, Nicholas C. |
  21. Waters, Paul |
  22. Fedrigo, Olivier |
  23. Jarvis, Erich D. |
  24. Gemmell, Neil |
  25. Alexander, Alana |
  26. Hore, Timothy |
1000 Erscheinungsjahr 2023
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2023-10-17
1000 Erschienen in
1000 Quellenangabe
  • 14(1):6364
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2023
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1038/s41467-023-41784-8 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10582058/ |
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1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:p>Combining genome assembly with population and functional genomics can provide valuable insights to development and evolution, as well as tools for species management. Here, we present a chromosome-level genome assembly of the common brushtail possum (<jats:italic>Trichosurus vulpecula</jats:italic>), a model marsupial threatened in parts of their native range in Australia, but also a major introduced pest in New Zealand. Functional genomics reveals post-natal activation of chemosensory and metabolic genes, reflecting unique adaptations to altricial birth and delayed weaning, a hallmark of marsupial development. Nuclear and mitochondrial analyses trace New Zealand possums to distinct Australian subspecies, which have subsequently hybridised. This admixture allowed phasing of parental alleles genome-wide, ultimately revealing at least four genes with imprinted, parent-specific expression not yet detected in other species (<jats:italic>MLH1</jats:italic>, <jats:italic>EPM2AIP1</jats:italic>, <jats:italic>UBP1</jats:italic> and <jats:italic>GPX7</jats:italic>). We find that reprogramming of possum germline imprints, and the wider epigenome, is similar to eutherian mammals except onset occurs after birth. Together, this work is useful for genetic-based control and conservation of possums, and contributes to understanding of the evolution of novel mammalian epigenetic traits.</jats:p>
1000 Sacherschließung
lokal Marsupialia [MeSH]
lokal Australia [MeSH]
lokal New Zealand/epidemiology [MeSH]
lokal Animals [MeSH]
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1000 Liste der Beteiligten
  1. https://orcid.org/0000-0001-7704-1263|https://frl.publisso.de/adhoc/uri/T3J0ZWdhLVJlY2FsZGUsIE9zY2Fy|https://frl.publisso.de/adhoc/uri/TGFpcmQsIE1lbGFuaWUgSy4=|https://orcid.org/0000-0002-1037-0350|https://frl.publisso.de/adhoc/uri/UmljaGFyZHNvbiwgS3lsZSBTLg==|https://orcid.org/0000-0003-2712-5797|https://frl.publisso.de/adhoc/uri/S3lsZSwgQnJ1Y2U=|https://frl.publisso.de/adhoc/uri/TWNJc2FhYy1XaWxsaWFtcywgQnJvb2tlIEUu|https://orcid.org/0000-0002-5348-2731|https://frl.publisso.de/adhoc/uri/dmFuIEhlZXppaywgWW9sYW5kYQ==|https://frl.publisso.de/adhoc/uri/QWRhbXMsIEFteSBMLg==|https://orcid.org/0000-0003-0991-6827|https://frl.publisso.de/adhoc/uri/SGFhc2UsIEJldHRpbmE=|https://frl.publisso.de/adhoc/uri/TW91bnRjYXN0bGUsIEphY3F1ZWx5bg==|https://frl.publisso.de/adhoc/uri/RHJpbGxlciwgTWF4aW1pbGlhbg==|https://frl.publisso.de/adhoc/uri/Q29sbGlucywgSm9hbm5h|https://orcid.org/0000-0003-2237-513X|https://orcid.org/0000-0003-4581-0325|https://orcid.org/0000-0003-4957-7807|https://frl.publisso.de/adhoc/uri/TGlzdGVyLCBOaWNob2xhcyBDLg==|https://orcid.org/0000-0002-4689-8747|https://frl.publisso.de/adhoc/uri/RmVkcmlnbywgT2xpdmllcg==|https://frl.publisso.de/adhoc/uri/SmFydmlzLCBFcmljaCBELg==|https://orcid.org/0000-0003-0671-3637|https://orcid.org/0000-0002-6456-7757|https://orcid.org/0000-0002-6735-225X
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