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1000
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Abstract/Summary
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<jats:title>Abstract</jats:title><jats:sec>
<jats:title>Background</jats:title>
<jats:p>Malignant tumors of the esophagus are the sixth leading cause of cancer-related deaths worldwide. Postoperative leakage of the esophago-gastrostomy leads to mediastinal sepsis, which is still associated with a high morbidity and mortality rate. The aim of this study was to describe the endoscopic view of the different severity grades of an anastomotic leakage.</jats:p>
</jats:sec><jats:sec>
<jats:title>Methods</jats:title>
<jats:p>Patients</jats:p>
<jats:p>Between June 2016 and September 2018, 144 patients were operated upon in the Department of Surgery, University of Munich, Germany.</jats:p>
<jats:p>Among these patients, 34 (23.6%) presented with a leakage of the anastomosis.</jats:p>
<jats:p>Endoscopy</jats:p>
<jats:p>In this retrospective analysis, the focus is to describe different patterns of leakage of the anastomosis.</jats:p>
</jats:sec><jats:sec>
<jats:title>Results</jats:title>
<jats:p>We studied 34 patients in whom post-esophagectomy leakage of the anastomosis was detected and treated with an endoluminal vacuum sponge system. The leakage healed in 26 of 29 patients (success rate 89.7%).</jats:p>
<jats:p>With the increasing severity of leakage, the treatment time and the in-hospital mortality correspondingly increased. Furthermore, the incidence of the development of a fistula to the tracheobronchial system increased with higher grades of leakage.</jats:p>
</jats:sec><jats:sec>
<jats:title>Conclusions</jats:title>
<jats:p>Exact descriptions of leakage are necessary to compare the cases and to prove post-treatment improvement. This is, to our knowledge, the first publication to present a leakage grading score in patients after esophagectomy including reconstruction with a gastric tube.</jats:p>
<jats:p>This new grading system needs to be tested in further analyses, with a special focus on prospective analysis.</jats:p>
</jats:sec>
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1000
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Hinweis
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DeepGreen-ID: ce8f33ec05904b6cb3f3ef951d9df9a8 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
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