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1000 Titel
  • Drug landscape in patients receiving general outpatient palliative care in Germany: results from a retrospective analysis of 10,464 patients
1000 Autor/in
  1. Loosen, Sven H. |
  2. Schwartz, Jacqueline |
  3. Grewe, Steven |
  4. Krieg, Sarah |
  5. Krieg, Andreas |
  6. Luedde, Tom |
  7. Batzler, Yann-Nicolas |
  8. Kostev, Karel |
  9. Neukirchen, Martin |
  10. Roderburg, Christoph |
1000 Verlag
  • BioMed Central
1000 Erscheinungsjahr 2023
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2023-08-19
1000 Erschienen in
1000 Quellenangabe
  • 22(1):118
1000 Copyrightjahr
  • 2023
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12904-023-01231-3 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10439623/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>According to § 27 and § 87 1b of the German Social Code, Book V, general outpatient palliative care (GOPC) aims to promote, maintain, and improve the quality of life and self-determination of seriously ill people. It should enable them to live in dignity until death in their preferred environment. Instead of a curative approach GOPC treatment focuses on the multiprofessional objective of alleviating symptoms and suffering on a case-by-case basis using medication or other measures, as well as the management of an individual treatment plan. The aim of this study was therefore to investigate to what extent medication differs from 12 months prior GOPC treatment within 12 months following GOPC treatment.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>A retrospective database cross sectional study based on the IQVIA Disease Analyzer (DA) was performed, including adult patients with cancer diagnosis and at least one documentation of palliative support between January 1st, 2018 and December 31st, 2021, in 805 general practices (GP).</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>The results of this study show, that in the context of general general outpatient palliative care, there is a significant increase in the prescription of opioids (18.3% vs. 37.7%), sedatives (7.8% vs. 16.2%) and antiemetics (5.3% vs. 9.7%), as well as a significant reduction in other medications such as statins (21.4% vs. 11.5%), proton pump inhibitors (PPI) (41.2% vs. 35.3%), or antihypertensives (57.5% vs. 46.6%).</jats:p> </jats:sec><jats:sec> <jats:title>Conclusions</jats:title> <jats:p>Our results support the role of GOPC as an important element in improving pharmacological symptom control and deprescription to improve quality of life of patients at the end of their life.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Medication
lokal Adult [MeSH]
lokal Humans [MeSH]
lokal Palliative Care [MeSH]
lokal Retrospective Studies [MeSH]
lokal Opioids
lokal Outpatient palliative care
lokal Cross-Sectional Studies [MeSH]
lokal Sedatives
lokal Prescription
lokal Outpatients [MeSH]
lokal Quality of Life [MeSH]
lokal Research
lokal Germany [MeSH]
lokal Deprescription
lokal Antiemetics
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/TG9vc2VuLCBTdmVuIEgu|https://frl.publisso.de/adhoc/uri/U2Nod2FydHosIEphY3F1ZWxpbmU=|https://frl.publisso.de/adhoc/uri/R3Jld2UsIFN0ZXZlbg==|https://frl.publisso.de/adhoc/uri/S3JpZWcsIFNhcmFo|https://frl.publisso.de/adhoc/uri/S3JpZWcsIEFuZHJlYXM=|https://frl.publisso.de/adhoc/uri/THVlZGRlLCBUb20=|https://frl.publisso.de/adhoc/uri/QmF0emxlciwgWWFubi1OaWNvbGFz|https://frl.publisso.de/adhoc/uri/S29zdGV2LCBLYXJlbA==|https://frl.publisso.de/adhoc/uri/TmV1a2lyY2hlbiwgTWFydGlu|https://frl.publisso.de/adhoc/uri/Um9kZXJidXJnLCBDaHJpc3RvcGg=
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