Engineering homoeologs provide a fine scale for quantitative traits in polyploid

  1. Lee, Eun Song
  2. Heo, Jung
  3. Bang, Woo Young
  4. Chougule, Kapeel M
  5. Waminal, Nomar Espinosa ORCID logo
  6. Hong, Nguyen Thi
  7. Kim, Min Ji
  8. Beak, Hong Kwan
  9. Kim, Yong Jun
  10. Priatama, Ryza A
  11. Jang, Ji In
  12. Cha, Kang Il
  13. Son, Seung Han
  14. Rajendran, Sujeevan
  15. Choo, Young-Kug
  16. Bae, Jong Hyang
  17. Kim, Chul Min
  18. Lee, Young Koung
  19. Bae, Sangsu
  20. Jones, Jonathan D G
  21. Sohn, Kee Hoon
  22. Lee, Jiyoung
  23. Kim, Hyun Hee
  24. Hong, Jong Chan
  25. Ware, Doreen
  26. Kim, Keunhwa
  27. Park, Soon Ju ORCID logo

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WeightNameValue
1000 Titel
  • Engineering homoeologs provide a fine scale for quantitative traits in polyploid
1000 Autor/in
  1. Lee, Eun Song |
  2. Heo, Jung |
  3. Bang, Woo Young |
  4. Chougule, Kapeel M |
  5. Waminal, Nomar Espinosa |
  6. Hong, Nguyen Thi |
  7. Kim, Min Ji |
  8. Beak, Hong Kwan |
  9. Kim, Yong Jun |
  10. Priatama, Ryza A |
  11. Jang, Ji In |
  12. Cha, Kang Il |
  13. Son, Seung Han |
  14. Rajendran, Sujeevan |
  15. Choo, Young-Kug |
  16. Bae, Jong Hyang |
  17. Kim, Chul Min |
  18. Lee, Young Koung |
  19. Bae, Sangsu |
  20. Jones, Jonathan D G |
  21. Sohn, Kee Hoon |
  22. Lee, Jiyoung |
  23. Kim, Hyun Hee |
  24. Hong, Jong Chan |
  25. Ware, Doreen |
  26. Kim, Keunhwa |
  27. Park, Soon Ju |
1000 Erscheinungsjahr 2023
1000 LeibnizOpen
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2023-08-02
1000 Erschienen in
1000 Quellenangabe
  • 21(12):2458-2472
1000 FRL-Sammlung
1000 Copyrightjahr
  • 2023
1000 Lizenz
1000 Verlagsversion
  • https://dx.doi.org/10.1111/pbi.14141 |
  • https://pmc.ncbi.nlm.nih.gov/articles/PMC10651150/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • Numerous staple crops exhibit polyploidy and are difficult to genetically modify. However, recent advances in genome sequencing and editing have enabled polyploid genome engineering. The hexaploid black nightshade species Solanum nigrum has immense potential as a beneficial food supplement. We assembled its genome at the scaffold level. After functional annotations, we identified homoeologous gene sets, with similar sequence and expression profiles, based on comparative analyses of orthologous genes with close diploid relatives Solanum americanum and S. lycopersicum. Using CRISPR-Cas9-mediated mutagenesis, we generated various mutation combinations in homoeologous genes. Multiple mutants showed quantitative phenotypic changes based on the genotype, resulting in a broad-spectrum effect on the quantitative traits of hexaploid S. nigrum. Furthermore, we successfully improved the fruit productivity of Boranong, an orphan cultivar of S. nigrum suggesting that engineering homoeologous genes could be useful for agricultural improvement of polyploid crops.
1000 Sacherschließung
lokal quantitative traits
lokal homoeologous gene editing
lokal agricultural improvement
lokal polyploid
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/TGVlLCBFdW4gU29uZyA=|https://frl.publisso.de/adhoc/uri/SGVvLCBKdW5n|https://frl.publisso.de/adhoc/uri/QmFuZywgV29vIFlvdW5n|https://frl.publisso.de/adhoc/uri/Q2hvdWd1bGUsIEthcGVlbCBN|https://orcid.org/0000-0001-5119-152X|https://frl.publisso.de/adhoc/uri/SG9uZywgTmd1eWVuIFRoaQ==|https://frl.publisso.de/adhoc/uri/S2ltLCBNaW4gSmkg|https://frl.publisso.de/adhoc/uri/QmVhaywgSG9uZyBLd2Fu|https://frl.publisso.de/adhoc/uri/S2ltLCBZb25nIEp1biA=|https://frl.publisso.de/adhoc/uri/UHJpYXRhbWEsIFJ5emEgQQ==|https://frl.publisso.de/adhoc/uri/SmFuZywgSmkgSW4=|https://frl.publisso.de/adhoc/uri/Q2hhLCBLYW5nIElsICA=|https://frl.publisso.de/adhoc/uri/U29uLCBTZXVuZyBIYW4=|https://frl.publisso.de/adhoc/uri/UmFqZW5kcmFuLCBTdWplZXZhbg==|https://frl.publisso.de/adhoc/uri/Q2hvbywgWW91bmctS3Vn|https://frl.publisso.de/adhoc/uri/QmFlLCBKb25nIEh5YW5n|https://frl.publisso.de/adhoc/uri/S2ltLCBDaHVsIE1pbiA=|https://frl.publisso.de/adhoc/uri/TGVlLCBZb3VuZyBLb3VuZw==|https://frl.publisso.de/adhoc/uri/QmFlLCBTYW5nc3Ug|https://frl.publisso.de/adhoc/uri/Sm9uZXMsIEpvbmF0aGFuIEQgRw==|https://frl.publisso.de/adhoc/uri/U29obiwgS2VlIEhvb24g|https://frl.publisso.de/adhoc/uri/TGVlLCBKaXlvdW5nIA==|https://frl.publisso.de/adhoc/uri/S2ltLCBIeXVuIEhlZQ==|https://frl.publisso.de/adhoc/uri/SG9uZywgSm9uZyBDaGFu|https://frl.publisso.de/adhoc/uri/V2FyZSwgRG9yZWVu|https://frl.publisso.de/adhoc/uri/S2ltLCBLZXVuaHdh|https://orcid.org/0000-0002-8525-5891
1000 Label
1000 Förderer
  1. National Research Foundation of Korea |
  2. USDA Rural Development |
1000 Fördernummer
  1. 2020R1A6A1A03044344;2021R1C1C2006483;2020R1A2C1101915
  2. 80622100044000D
1000 Förderprogramm
  1. -
  2. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer National Research Foundation of Korea |
    1000 Förderprogramm -
    1000 Fördernummer 2020R1A6A1A03044344;2021R1C1C2006483;2020R1A2C1101915
  2. 1000 joinedFunding-child
    1000 Förderer USDA Rural Development |
    1000 Förderprogramm -
    1000 Fördernummer 80622100044000D
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6489194.rdf
1000 Erstellt am 2024-11-27T13:53:02.143+0100
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1000 Bearbeitet von 317
1000 Zuletzt bearbeitet 2025-02-24T14:33:49.645+0100
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1000 Vgl. frl:6489194
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  1. oai:frl.publisso.de:frl:6489194 |
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