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1000 Titel
  • Portosystemic Hepatic Encephalopathy Scores (PHES) differ between Danish and German healthy populations despite their geographical and cultural similarities
1000 Autor/in
  1. Munk Lauridsen, Mette |
  2. Grønkjær, Lea Ladegaard |
  3. Holm Atkins, Jeppe |
  4. Mikkelsen, Stine Ulrik |
  5. Svensson, Tintin |
  6. Kimer, Nina |
  7. Hecker, Hartmut |
  8. Berg-Beckhoff, Gabriele |
  9. Weissenborn, Karin |
  10. Vilstrup, Hendrik |
1000 Verlag Springer US
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-07-17
1000 Erschienen in
1000 Quellenangabe
  • 39(6):1149-1155
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s11011-024-01380-1 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11349773/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:p>Minimal hepatic encephalopathy (MHE) is common in liver cirrhosis and is identified by psychometric tests. The portosystemic hepatic encephalopathy score (PHES) is the most widely used and serves as an inter-study comparator. PHES has not been standardised for use in the Danish population, where German normal values have been applied until now based on the notion that the populations are comparable. This study aimed to evaluate if German PHES normal values can be applied in the Danish population and establish Danish normal values if needed. 200 Danish and 217 German healthy persons underwent Number Connection Test A and B (NCT), Line Tracing Test (LTT), Digit Symbol Test (DST), and Serial Dotting Test (SDT), and based on performance, PHES was calculated. German and Danish PHES performance declined with age in all subtests but more rapidly in Danes. Both German and Danish norms were impacted by gender and education, but to a different extent in the single tests of the test battery. Accordingly, there was a need for specific Danish normal values, which are presented here. Applying the new Danish normal values instead of the German in patients with cirrhosis yielded a lower percentage of out-of-norm performances (58% vs. 66%) and, hence, a lower prevalence of MHE. Danes and Germans perform differently on PHES, and therefore, normal German values cannot be used in Danish patients. Danish normal values are presented here and yield a lower number of ‘out of norm’ performances.</jats:p>
1000 Sacherschließung
lokal Denmark/epidemiology [MeSH]
lokal Denmark
lokal Female [MeSH]
lokal Liver Cirrhosis/diagnosis [MeSH]
lokal Aged [MeSH]
lokal Reference Values [MeSH]
lokal Adult [MeSH]
lokal Hepatic Encephalopathy/diagnosis [MeSH]
lokal Humans [MeSH]
lokal Normality tables
lokal Middle Aged [MeSH]
lokal Germany/epidemiology [MeSH]
lokal Hepatic Encephalopathy/epidemiology [MeSH]
lokal Psychometrics [MeSH]
lokal Male [MeSH]
lokal Research
lokal Hepatic encephalopathy
lokal Young Adult [MeSH]
lokal Cognition
lokal Cross-Cultural Comparison [MeSH]
lokal Hepatic Encephalopathy/psychology [MeSH]
lokal Liver cirrhosis
lokal Neuropsychological Tests [MeSH]
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0003-0586-8549|https://frl.publisso.de/adhoc/uri/R3LDuG5rasOmciwgTGVhIExhZGVnYWFyZA==|https://orcid.org/0000-0002-2928-353X|https://orcid.org/0000-0003-2104-9201|https://frl.publisso.de/adhoc/uri/U3ZlbnNzb24sIFRpbnRpbg==|https://orcid.org/0000-0002-4807-1575|https://orcid.org/0000-0002-1780-1328|https://orcid.org/0000-0003-1614-938X|https://orcid.org/0000-0002-1157-8938|https://orcid.org/0000-0002-9903-407X
1000 Hinweis
  • DeepGreen-ID: dcda1175a19b4733bc9d2524c9d80dd1 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
1000 Label
1000 Förderer
  1. Syddansk Universitet |
1000 Fördernummer
  1. -
1000 Förderprogramm
  1. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Syddansk Universitet |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
1000 Beschrieben durch
1000 @id frl:6494216.rdf
1000 Erstellt am 2025-02-04T01:37:07.062+0100
1000 Erstellt von 322
1000 beschreibt frl:6494216
1000 Zuletzt bearbeitet 2025-09-13T03:08:34.992+0200
1000 Objekt bearb. Sat Sep 13 03:08:34 CEST 2025
1000 Vgl. frl:6494216
1000 Oai Id
  1. oai:frl.publisso.de:frl:6494216 |
1000 Sichtbarkeit Metadaten public
1000 Sichtbarkeit Daten public
1000 Gegenstand von

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