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1000 Titel
  • Acceptance and feasibility of a low-threshold and substitution services-based periodical monitoring system for blood-borne and sexually transmitted infections among people who inject drugs in Germany: a mixed-methods analysis
1000 Autor/in
  1. Krings, Amrei |
  2. Steffen, Gyde |
  3. Zimmermann, Ruth |
  4. the DRUCK 2.0-study group |
1000 Verlag BioMed Central
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-03-14
1000 Erschienen in
1000 Quellenangabe
  • 21(1):62
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12954-024-00977-0 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10938743/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>To reach the global elimination goals of viral hepatitis B and C (HBC, HCV), human immunodeficiency virus (HIV) and other sexually transmitted infections as a public health threat by 2030, monitoring is needed. Staff members of drug services and opioid substitution treatment (OST) practices in Berlin and Bavaria recruited clients for a pilot study addressing the respective infections among people who injected drugs (PWID) in Germany, 2021/2022. Participants filled a questionnaire and were tested for HBV, HCV, HIV and syphilis using dried blood spots (DBS). We evaluated the study design to implement a feasible and accepted nationwide periodical monitoring among PWID and serve as an example for the implementation of similar monitoring systems in other countries.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>A mixed-methods design was used, including focus group discussions with study participants and staff members and a semi-quantitative questionnaire filled by the latter. Aspects covered were the setting for recruitment, study preparation for staff members, willingness of clients to participate, the study questionnaire, blood collection and return of results.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>The majority (96%) of 668 study participants were recruited in low-threshold services, drug consumption rooms and OST-practices. Flexibility of recruiting study participants during routine work or testing weeks/days was important to the facilities. Collaborations with local AIDS services helped cope with the work load of data collection. The need to train staff for DBS collection was highlighted. Study participants welcomed the testing opportunity in familiar places. Study participants frequently needed assistance to complete the study questionnaire. Return of results was considered as ethically mandatory by staff members but referral to treatment remained challenging.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusions</jats:title> <jats:p>For a successful monitoring time flexibility and adequate training are essential. Individual benefits for study participants by receiving their test results should be ensured and referral networks with infectiology practices may increase number of infected PWID receiving treatment. Overall, the evaluation confirmed that a monitoring through drug services and OST-practices is feasible and well accepted in Germany. Beyond that it shows important lessons learnt for the implementation in other countries.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Hepatitis C/epidemiology [MeSH]
lokal Humans [MeSH]
lokal People who inject drugs
lokal Infectious diseases
lokal Germany
lokal Feasibility Studies [MeSH]
lokal Feasibility
lokal Sexually Transmitted Diseases [MeSH]
lokal Research
lokal Pilot Projects [MeSH]
lokal Acceptance
lokal HIV Infections/prevention
lokal Substance Abuse, Intravenous/drug therapy [MeSH]
lokal Monitoring
lokal Drug Users [MeSH]
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://frl.publisso.de/adhoc/uri/S3JpbmdzLCBBbXJlaQ==|https://frl.publisso.de/adhoc/uri/U3RlZmZlbiwgR3lkZQ==|https://frl.publisso.de/adhoc/uri/WmltbWVybWFubiwgUnV0aA==|https://frl.publisso.de/adhoc/uri/dGhlIERSVUNLIDIuMC1zdHVkeSBncm91cA==
1000 Hinweis
  • DeepGreen-ID: f237440ba4ec46bf98aa2f7a9f648529 ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
1000 Label
1000 Förderer
  1. German Federal Ministry of Health |
  2. Robert Koch Institut |
1000 Fördernummer
  1. -
  2. -
1000 Förderprogramm
  1. -
  2. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer German Federal Ministry of Health |
    1000 Förderprogramm -
    1000 Fördernummer -
  2. 1000 joinedFunding-child
    1000 Förderer Robert Koch Institut |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
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1000 @id frl:6495736.rdf
1000 Erstellt am 2025-02-04T10:43:41.386+0100
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