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1000 Titel
  • Cochlear implantation in patients with inner ear schwannomas: a systematic review and meta-analysis of audiological outcomes
1000 Autor/in
  1. Iannacone, Francesco Pio |
  2. Rahne, Torsten |
  3. zanoletti, elisabetta |
  4. Plontke, Stefan |
1000 Verlag
  • Springer Berlin Heidelberg
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-07-11
1000 Erschienen in
1000 Quellenangabe
  • 281(12):6175-6186
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1007/s00405-024-08818-3 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11564253/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Purpose</jats:title> <jats:p>In patients with inner ear schwannomas (IES), reports on hearing rehabilitation with cochlear implants (CI) have increased over the past decade, most of which are case reports or small case series. The aim of this study is to systematically review the reported hearing results with CI in patients with IES considering the different audiologic outcome measures used in different countries.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>According to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guideline, a search of published literature was conducted. We included patients with IES (primary or with secondary extension from the internal auditory canal (IAC) to the inner ear, sporadic or NF2 related) undergoing cochlear implantation with or without tumour removal. The audiological results were divided into the categories “monosyllables”, “disyllables”, “multisyllabic words or numbers”, and “sentences”.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>Predefined audiological outcome measures were available from 110 patients and 111 ears in 27 reports. The mean recognition scores for monosyllabic words with CI were 55% (SD: 24), for bisyllabic words 61% (SD: 36), for multisyllabic words and numbers 87% (SD: 25), and 71% (SD: 30) for sentences. Results from for multisyllabic words and numbers in general showed a tendency towards a ceiling effect. Possible risk factors for performance below average were higher complexity tumours (inner ear plus IAC/CPA), NF2, CI without tumour removal (“CI through tumour”), and sequential cochlear implantation after tumour removal (staged surgery).</jats:p> </jats:sec><jats:sec> <jats:title>Conclusion</jats:title> <jats:p>Hearing loss in patients with inner ear schwannomas can be successfully rehabilitated with CI with above average speech performance in most cases. Cochlear implantation thus represents a valuable option for hearing rehabilitation also in patients with IES while at the same time maintaining the possibility of MRI follow-up. Further studies should investigate possible risk factors for poor performance. Audiological tests and outcome parameters should be reported in detail and ideally be harmonized to allow better comparison between languages.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Ear Neoplasms/complications [MeSH]
lokal Vestibular schwannoma
lokal Ear Neoplasms/surgery [MeSH]
lokal Intracochlear
lokal Humans [MeSH]
lokal Treatment Outcome [MeSH]
lokal Neuroma, Acoustic/surgery [MeSH]
lokal Review Article
lokal Cochlear implant
lokal Neuroma, Acoustic/complications [MeSH]
lokal Schwannoma
lokal Intralabyrinthine
lokal Neurilemmoma/complications [MeSH]
lokal Neurilemmoma/surgery [MeSH]
lokal Cochlear Implantation/methods [MeSH]
lokal Inner ear schwannoma
lokal Acoustic neuroma
lokal Skull base surgery
lokal Cochlear Implants [MeSH]
lokal Ear, Inner/surgery [MeSH]
lokal Neuroma, Acoustic/physiopathology [MeSH]
lokal Speech Perception [MeSH]
lokal Neurotology
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0002-1324-9484|https://orcid.org/0000-0003-1859-5623|https://orcid.org/0000-0001-5562-5292|https://orcid.org/0000-0002-5424-7688
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1000 Label
1000 Förderer
  1. Martin-Luther-Universität Halle-Wittenberg |
1000 Fördernummer
  1. -
1000 Förderprogramm
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1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Martin-Luther-Universität Halle-Wittenberg |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
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1000 Erstellt am 2025-02-04T11:01:12.546+0100
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