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1000 Titel
  • Consideration of inequalities in effectiveness trials of mHealth applications – a systematic assessment of studies from an umbrella review
1000 Autor/in
  1. Abdelmalak, Nancy |
  2. Burns, Jacob |
  3. Suhlrie, Laura |
  4. Laxy, Michael |
  5. Stephan, Anna-Janina |
1000 Verlag
  • BioMed Central
1000 Erscheinungsjahr 2024
1000 Publikationstyp
  1. Artikel |
1000 Online veröffentlicht
  • 2024-09-11
1000 Erschienen in
1000 Quellenangabe
  • 23(1):181
1000 Copyrightjahr
  • 2024
1000 Lizenz
1000 Verlagsversion
  • https://doi.org/10.1186/s12939-024-02267-4 |
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11389088/ |
1000 Publikationsstatus
1000 Begutachtungsstatus
1000 Sprache der Publikation
1000 Abstract/Summary
  • <jats:title>Abstract</jats:title><jats:sec> <jats:title>Background</jats:title> <jats:p>The growing use of mobile health applications (apps) for managing diabetes and hypertension entails an increased need to understand their effectiveness among different population groups. It is unclear if efficacy and effectiveness trials currently provide evidence of differential effectiveness, and if they do, a summary of such evidence is missing. Our study identified to what extent sociocultural and socioeconomic inequalities were considered in effectiveness trials of mobile health apps in diabetic and hypertensive patients and if these inequalities moderated app effectiveness.</jats:p> </jats:sec><jats:sec> <jats:title>Methods</jats:title> <jats:p>We built on our recent umbrella review that synthesized systematic reviews (SRs) of randomized controlled trials (RCTs) on the effectiveness of health apps. Using standard SR methodologies, we identified and assessed all primary RCTs from these SRs that focused on diabetes and/or hypertension and reported on health-related outcomes and inequality-related characteristics across intervention arms. We used the PROGRESS-Plus framework to define inequality-related characteristics that affect health opportunities and outcomes. We used harvest plots to summarize the subgroups (stratified analyses or interaction terms) on moderating effects of PROGRESS-Plus. We assessed study quality using the Risk of Bias 2 tool.</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>We included 72 published articles of 65 unique RCTs. Gender, age, and education were the most frequently described PROGRESS-Plus characteristics at baseline in more than half of the studies. Ethnicity and occupation followed in 21 and 15 RCTs, respectively. Seven trials investigated the moderating effect of age, gender or ethnicity on app effectiveness through subgroup analyses. Results were equivocal and covered a heterogenous set of outcomes. Results showed some concerns for a high risk of bias, mostly because participants could not be blinded to their intervention allocation.</jats:p> </jats:sec><jats:sec> <jats:title>Conclusions</jats:title> <jats:p>Besides frequently available gender, age, and education descriptives, other relevant sociocultural or socioeconomic characteristics were neither sufficiently reported nor analyzed. We encourage researchers to investigate how these characteristics moderate the effectiveness of health apps to better understand how effect heterogeneity for apps across different sociocultural or socioeconomic groups affects inequalities, to support more equitable management of non-communicable diseases in increasingly digitalized systems.</jats:p> </jats:sec><jats:sec> <jats:title>Registration</jats:title> <jats:p><jats:ext-link xmlns:xlink='http://www.w3.org/1999/xlink' ext-link-type='uri' xlink:href='https://osf.io/89dhy/'>https://osf.io/89dhy/</jats:ext-link>.</jats:p> </jats:sec>
1000 Sacherschließung
lokal Systematic Review
lokal PROGRESS-Plus
lokal Telemedicine [MeSH]
lokal Female [MeSH]
lokal Diabetes mellitus
lokal Humans [MeSH]
lokal Systematic review
lokal mHealth
lokal Mobile Applications/standards [MeSH]
lokal Socioeconomic Factors [MeSH]
lokal Diabetes Mellitus/therapy [MeSH]
lokal Randomized Controlled Trials as Topic [MeSH]
lokal Male [MeSH]
lokal Equality
lokal Hypertension/therapy [MeSH]
lokal Healthcare Disparities [MeSH]
lokal Social determinants of health
lokal Equity
lokal Hypertension
1000 Fächerklassifikation (DDC)
1000 Liste der Beteiligten
  1. https://orcid.org/0000-0003-3980-907X|https://orcid.org/0000-0003-4015-6862|https://orcid.org/0000-0002-8810-7181|https://orcid.org/0000-0001-8775-7417|https://orcid.org/0000-0002-6438-2058
1000 Hinweis
  • DeepGreen-ID: c2932e8b0e754bc185391630cf379fde ; metadata provieded by: DeepGreen (https://www.oa-deepgreen.de/api/v1/), LIVIVO search scope life sciences (http://z3950.zbmed.de:6210/livivo), Crossref Unified Resource API (https://api.crossref.org/swagger-ui/index.html), to.science.api (https://frl.publisso.de/), ZDB JSON-API (beta) (https://zeitschriftendatenbank.de/api/), lobid - Dateninfrastruktur für Bibliotheken (https://lobid.org/resources/search)
1000 Label
1000 Förderer
  1. Technische Universität München |
1000 Fördernummer
  1. -
1000 Förderprogramm
  1. -
1000 Dateien
1000 Förderung
  1. 1000 joinedFunding-child
    1000 Förderer Technische Universität München |
    1000 Förderprogramm -
    1000 Fördernummer -
1000 Objektart article
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1000 @id frl:6496578.rdf
1000 Erstellt am 2025-02-04T14:07:07.126+0100
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